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International symposium on biology of cancer prevention and treatment
The International Symposium on ‘Biology of Cancer Prevention and Treatment’ was held in Beijing, People's Republic of China, 1–3 November 1999, under the joint sponsorship of the International Union A...
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Kurt S Zänker
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S1-S4
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Molecular and cytogenetic alterations in early stage of carcinogenesis of human lung
Abstract: In an attempt to reveal the genetic and epigenetic abnormalities in early stage of carcinogenesis of human lung cancer, a human bronchial epithelial cell line was immortalized by transfectio...
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Shujun Cheng,
Yanning Gao,
Xiangyang Dong,
Yongjie Lu,
Qian An,
Tong Tong,
Yongjun Wang
et al.
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S5-S10
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Predictive laboratory diagnostics in oncology utilizing blood-borne cancer cells – current best practice and unmet needs
Abstract: The aim of laboratory diagnostics in oncology is to improve the clinical outcome of cancer by allowing earlier detection. Molecular knowledge of cancer should increase the number of risk and...
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Burkhard H. Brandt,
Hartmut Schmidt,
Gabriela de Angelis,
Kurt S. Zänker
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S11-S16
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Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications
Abstract: Alterations of the epidermal growth factor receptor (EGFR) occur frequently in malignant gliomas through gene amplification or rearrangement, especially in a large fraction of de novo type g...
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Motoo Nagane,
Hong Lin,
Webster K. Cavenee,
H.-J.Su Huang
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S17-S21
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Regulating the neoplastic phenotype using engineered transcriptional repressors
Abstract: We have applied engineered transcriptional repressors to specifically inhibit disease gene-activated pathways in oncogenesis. We have demonstrated that synthetic repressors combining PAX3 DN...
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William J. Fredericks,
Kasirajan Ayyanathan,
Frank J. Rauscher
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S23-S32
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Potential use of antiviral l(−)nucleoside analogues for the prevention or treatment of viral associated cancers
Abstract: Several types of virus were found to have a strong association with different types of cancers. Thus, a selective antiviral compound without toxicity upon long-term usage will be useful not ...
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Yung-Chi Cheng
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S33-S37
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Prevention of entrance into G2 cell cycle phase by mimosine decreases locomotion of cells from the tumor cell line SW480
Abstract: Cellular proliferation of tumor cells is thought to impede migratory activity. Using continuous single cell migration analysis of the colon carcinoma cell line SW480 for up to 72 h, we were ...
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Britta S Kubens,
Bernd Niggemann,
Kurt S Zänker
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S39-S47
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Migration and metalloproteinases determine the invasive potential of mouse melanoma cells, but not melanin and telomerase
Abstract: The biological characteristic cell locomotion and invasion, melanin content, metalloproteinases and telomerase activity were studied in a parental mouse melanoma cell line B16 and two descen...
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Wanzhou Zhao,
Hongyan Liu,
Shaofeng Xu,
Frank Entschladen,
Bernd Niggemann,
Kurt S Zänker,
Rui Han
et al.
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S49-S55
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Author index
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S57
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