Cancer Letters
Volume 125, Issue 1 , Pages 9-15, 13 March 1998

Helicobacter pylori and gastric cancer in Croatia

  • Vladimir Babus

      Affiliations

    • Faculty of Medicine, A. Stampar School of Public Health, Rockefellerova 4, 10000 Zagreb, Croatia
    • Corresponding Author InformationCorresponding author. Tel.: +385 1 276822; fax: +385 1 275415.
    • ,
  • Marija Strnad

      Affiliations

    • Croatian National Institute of Public Health, Rockefellerova 7, 10000 Zagreb, Croatia
    • ,
  • Vladimir Presecki

      Affiliations

    • Faculty of Medicine, A. Stampar School of Public Health, Rockefellerova 4, 10000 Zagreb, Croatia
    • ,
  • Mirjana Katicic

      Affiliations

    • Internal Clinic, Merkur Hospital, Zajceva 19, 10000 Zagreb, Croatia
    • ,
  • Smilja Kalinic

      Affiliations

    • Faculty of Medicine, Salata 3b, 10000 Zagreb, Croatia
    • ,
  • Melita Balija

      Affiliations

    • Institute of Transfusional Medicine, Petrova 3, 10000 Zagreb, Croatia

Received 3 April 1997; received in revised form 16 September 1997; accepted 16 September 1997.

Abstract 

The seroprevalence of Helicobacter pylori infection was studied in a population from two areas of Croatia with significantly different average gastric cancer (GC) cumulative incidence and mortality rates. In a random sample of 456 blood sera from both areas, which was tested with the ELISA Helicobacter pylori-antibody test, 48.8% of people in the north and 53.3% in the south of the country were found to be infected. The difference between the two areas in the seroprevalence of the infection was not statistically significant, nor did their populations differ in age, sex, educational background, smoking habit or wine consumption. Our results do not point to any association between the prevalence of Helicobacter pylori infection and the level of cumulative incidence and GC mortality levels.

Keywords:  Seroprevalence, Helicobacter pylori infections, Gastric cancer, Association

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PII: S0304-3835(97)00446-1

Cancer Letters
Volume 125, Issue 1 , Pages 9-15, 13 March 1998

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