Cancer Letters
Volume 319, Issue 1 , Pages 98-108 , 1 June 2012

Blockade of ataxia telangiectasia mutated sensitizes hepatoma cell lines to sorafenib by interfering with Akt signaling

  • Shun Fujimaki

      Affiliations

    • Department of Medical Technology, Niigata University Graduate School of Health Sciences, Niigata, Japan
  • ,
  • Yasunobu Matsuda

      Affiliations

    • Department of Medical Technology, Niigata University Graduate School of Health Sciences, Niigata, Japan
    • Corresponding Author InformationCorresponding author. Address: Department of Medical Technology, Niigata University Graduate School of Health Sciences, 2-746 Asahimachi-dori, Niigata 951-8518, Japan. Tel.: +81 25 227 2357; fax: +81 25 227 0749.
  • ,
  • Toshifumi Wakai

      Affiliations

    • Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  • ,
  • Ayumi Sanpei

      Affiliations

    • Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  • ,
  • Masayuki Kubota

      Affiliations

    • Division of Pediatric Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  • ,
  • Masaaki Takamura

      Affiliations

    • Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  • ,
  • Satoshi Yamagiwa

      Affiliations

    • Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  • ,
  • Masahiko Yano

      Affiliations

    • Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  • ,
  • Shogo Ohkoshi

      Affiliations

    • Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
  • ,
  • Yutaka Aoyagi

      Affiliations

    • Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

Received 3 November 2011 ,Revised 21 December 2011 ,Accepted 22 December 2011.

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PII: S0304-3835(12)00043-2

doi: 10.1016/j.canlet.2011.12.043

Cancer Letters
Volume 319, Issue 1 , Pages 98-108 , 1 June 2012