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Cancer Letters
Volume 305, Issue 2
, Pages 200-217
, 28 June 2011
Viral hit and run-oncogenesis: Genetic and epigenetic scenarios
References
- . Transformation of primary hamster embryo fibroblasts by type 2 simplex virus: evidence for a “hit and run” mechanism. Br. J. Exp. Pathol. 1976;57:361–376
- . The oncogenic potential of herpes simplex viruses: evidence for a ‘hit-and-run’ mechanism. Nature. 1983;302:21–24
- . Alterations in the cellular phenotype induced by herpes simplex viruses. J. Med. Virol. 1990;31:36–42
- . Transformation of rodent fibroblasts by herpes simplex virus: presence of morphological transforming region 1 (MTR 1) is not required for the maintenance of the transformed state. Int. J. Cancer. 1992;51:754–760
- . Transformation of NIH 3T3 cells with cloned fragments of human cytomegalovirus strain AD169. J. Virol. 1982;43:83–91
- . Neoplastic transformation by a cloned human cytomegalovirus DNA fragment uniquely homologous to one of the transforming regions of herpes simplex virus type 2. Proc. Natl. Acad. Sci. USA. 1983;80:3826–3830
- . ‘Hit and run’ oncogenesis by human papillomavirus type 18 DNA. Acta Obstet. Gynecol. Scand. 1992;71:219–223
- . Human cytomagalovirus IE1 and IE2 proteins are mutagenic and mediate “hit-and-run” oncogenic transformation in cooperation with the adenovirus E1A proteins. Proc. Natl. Acad. Sci. USA. 1997;94:3341–3345
- . Combined herpes simplex virus type 2 and human papillomavirus type 16 or 18 deoxyribonucleic acid leads to oncogenic transformation. Am. J. Obstet. Gynecol. 1988;159:1251–1255
- . HSV-2-induced tumorigenicity in HPV16-immortalized human genital keratinocytes. Virology. 1990;177:777–779
- . Plasmid-induced “hit-and-run” tumorigenesis in Chinese hamster embryo fibroblast (CHEF) cells. Proc. Natl. Acad. Sci. USA. 1985;82:2839–2843
- . Viruses in human cancers. Eur. J. Cancer. 1999;35:1174–1181
- . Infectious agents and cancer: criteria for a causal relation. Semin. Cancer Biol. 2004;14:453–471
- . HBV induced carcinogenesis. J. Clin. Virol. 2005;34(Suppl. 1):S75–S78
- . Hepatitis B virus induced hepatocellular carcinoma. Cancer Lett. 2009;286:52–59
- . Hit-and-run mechanism of HBV-mediated progression to hepatocellular carcinoma. Tumori. 2005;91:241–247
- . Noncytolytic control of viral infections by the innate and adaptive immune response. Annu. Rev. Immunol. 2001;19:65–91
- . T cell response in hepatitis C virus infection. J. Clin. Virol. 2005;32:75–85
- . Role of hepatitis C virus proteins (C, NS3, NS5A) in hepatic oncogenesis. Hepatol. Res. 2008;38:1–26
- . Hepatitis C virus causes uncoupling of mitotic checkpoint and chromosomal polyploidy through the Rb pathway. J. Virol. 2009;83:12590–12600
- . Hepatitis C virus NS3/4A protein interacts with ATM, impairs DNA repair and enhances sensitivity to ionizing radiation. Virology. 2008;370:295–309
- . Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science. 1989;244:359–362
- . Hepatitis C virus infection in hepatocellular carcinoma. Detection of plus-strand and minus-strand viral RNA. Cancer. 1992;70:2255–2259
- . B-cell non-Hodgkin’s lymphoma and hepatitis C virus infection: a systematic review. Int. J. Cancer. 2004;111:1–8
- . Somatic hypermutation, clonal diversity, and preferential expression of the VH 51p1/VL kv325 immunoglobulin gene combination in hepatitis C virus-associated immunocytomas. Blood. 1998;91:2433–2442
- . Hepatitis C virus E2-CD81 interaction induces hypermutation of the immunoglobulin gene in B cells. J. Virol. 2005;79:8079–8089
- . Establishment of B-cell lymphoma cell lines persistently infected with hepatitis C virus in vivo and in vitro: the apoptotic effects of virus infection. J. Virol. 2003;77:2134–2146
- . Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling. Oncogene. 2007;26:5587–5595
- . A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations. Oncogene. 2009;28:469–478
- . Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes. Proc. Natl. Acad. Sci. USA. 2004;101:4262–4267
- . Regression of monoclonal B-cell expansion in patients affected by mixed cryoglobulinemia responsive to alpha-interferon therapy. Cancer. 1996;77:2604–2613
- . Regression of lymphoproliferative disorder after treatment for hepatitis C virus infection in a patient with partial trisomy 3, Bcl-2 overexpression, and type II cryoglobulinemia. Blood. 2002;99:2259–2261
- . Regression of splenic lymphoma with villous lymphocytes after treatment of hepatitis C virus infection. New Engl. J. Med. 2002;347:89–94
- . Treatment of HCV-related mantle-cell lymphoma with ribavirin and pegylated interferon Alfa. New Engl. J. Med. 2003;349:2078–2079
- . Viruses and lymphomas. New Engl. J. Med. 2002;347:78–79
- . Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus. Immunology. 2009;126:280–289
- . Human polyomaviruses and cancer: expanding repertoire. J. Dtsch. Dermatol. Ges. 2008;6:704–708
- . The role of polyomaviruses in human disease. Virology. 2009;384:266–273
- . Identification of a third human polyomavirus. J. Virol. 2007;81:4130–4136
- . Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathog. 2007;3:e64
- . Association of Merkel cell polyomavirus-specific antibodies with Merkel cell carcinoma. J. Natl. Cancer Inst. 2009;101:1510–1522
- . Clonal integration of a polyomavirus in human Merkel cell carcinoma. Science. 2008;319:1096–1100
- . T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus. Proc. Natl. Acad. Sci. USA. 2008;105:16272–16277
- . Reactivation and mutation of newly discovered WU, KI, and Merkel cell carcinoma polyomaviruses in immunosuppressed individuals. J. Infect. Dis. 2009;199:398–404
- . Merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Int. J. Cancer. 2009;125:356–361
- . Novel human polyomaviruses – re-emergence of a well known virus family as possible human carcinogens. Int. J. Cancer. 2008;123:247–250
- . Clinical factors associated with Merkel cell polyomavirus infection in Merkel cell carcinoma. J. Natl. Cancer Inst. 2009;101:938–945
- . Integration of high-risk human papillomavirus: a key event in cervical carcinogenesis?. J. Pathol. 2007;212:356–367
- . Potential mechanisms of the human polyomavirus JC in neural oncogenesis. J. Neuropathol. Exp. Neurol. 2008;67:729–740
- . Human neurotropic polyomavirus, JCV, and its role in carcinogenesis. Oncogene. 2003;22:5181–5191
- . Detection of JC virus DNA sequences and expression of viral T antigen and agnoprotein in esophageal carcinoma. Cancer. 2005;103:516–527
- . Glioblastoma multiforme with small cell neuronal-like component: association with human neurotropic JC virus. Acta Neuropathol. 2006;111:388–396
- . No evidence of an association of JC virus and colon neoplasia. Cancer Epidemiol. Biomark. Prev. 2004;13:662–666
- . Evidence for an association between JC virus and colorectal neoplasia. Cancer Epidemiol. Biomark. Prev. 2004;13:2285–2286
- . Induction of chromosomal instability in colonic cells by the human polyomavirus JC virus. Cancer Res. 2003;63:7256–7262
- . JC virus and colorectal cancer: a possible trigger in the chromosomal instability pathways. Curr. Opin. Gastroenterol. 2005;21:85–89
- . Oncogenic transformation by BK virus and association with human tumors. Oncogene. 2003;22:5192–5200
- . BK virus and human cancer: innocent until proven guilty. Semin. Cancer Biol. 2009;19:252–260
- . Adenovirus early E4 genes in viral oncogenesis. Oncogene. 2001;20:7847–7854
- . Integrated viral genomes can be lost from adenovirus type 12-induced hamster tumor cells in a clone-specific, multistep process with retention of the oncogenic phenotype. Virus Res. 1999;59:113–127
- . “Hit-and-run” transformation by adenovirus oncogenes. J. Virol. 2001;75:3089–3094
- . Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation. J. Virol. 2007;81:7034–7040
- . Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature. 2002;418:348–352
- . Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex. J. Virol. 2009;83:5329–5338
- . The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner. J. Biol. Chem. 2005;280:1474–1481
- . Epstein–Barr virus and cancer. Clin. Cancer Res. 2004;10:803–821
- . Epstein–Barr virus. In: Minarovits J, Gonczol E, Valyi-Nagy T editor. Latency Strategies of Herpesviruses. New York: Springer; 2007;p. 154–191
- . Epstein–Barr virus-associated epithelial and mesenchymal neoplasms. Hum. Pathol. 2008;39:473–483
- . Regulation and dysregulation of Epstein–Barr virus latency: implications for the development of autoimmune diseases. Autoimmunity. 2008;41:298–328
- . Spectrum of Epstein–Barr virus-related diseases: a pictorial review. Jpn. J. Radiol. 2009;27:4–19
- . Epigenetic dysregulation of the host cell genome in Epstein–Barr virus-associated neoplasia. Semin. Cancer Biol. 2009;19:158–164
- . Epigenetic dysregulation of Epstein–Barr virus latency and development of autoimmune disease. In: Ballestar E editors. Epigenetic Contributions in Autoimmune Disease. Austin: Landes Bioscience; 2010;p. 1–21
- . Immortalization of monkey epithelial cells by specific fragments of Epstein–Barr virus DNA. Nature. 1984;309:78–82
- . Epstein–Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt’s lymphoma. EMBO J. 2002;21:954–965
- . Epstein–Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3. J. Exp. Med. 2009;206:2091–2099
- . Final case reporting from the Ugandan prospective study of the relationship between EBV and Burkitt’s lymphoma. Int. J. Cancer. 1982;29:397–400
- . Hodgkin’s disease and Epstein–Barr virus. Altered antibody pattern before diagnosis. New Engl. J. Med. 1989;320:689–695
- . Elevated antibody titers to Epstein–Barr virus prior to the diagnosis of Epstein–Barr-virus-associated gastric adenocarcinoma. Int. J. Cancer. 1995;60:642–644
- . Serological mass survey for early detection of nasopharyngeal carcinoma in Wuzhou City, China. Int. J. Cancer. 1982;29:139–141
- . Epstein–Barr virus with heterogeneous DNA disrupts latency. J. Virol. 1984;50:174–182
- . P3HR-1 Epstein–Barr virus with heterogeneous DNA is an independent replicon maintained by cell-to-cell spread. J. Virol. 1985;54:45–52
- . Points of recombination in Epstein–Barr virus (EBV) strain P3HR-1-derived heterogeneous DNA as indexes to EBV DNA recombinogenic events in vivo. J. Virol. 2008;82:11516–11525
- . Defective viral DNA in Epstein–Barr virus-associated oral hairy leukoplakia. J. Virol. 1990;64:397–400
- . High levels of Epstein–Barr virus DNA in latently infected gastric adenocarcinoma. Lab. Invest. 2009;89:80–90
- . A nuclear matrix attachment region organizes the Epstein–Barr viral plasmid in Raji cells into a single DNA domain. EMBO J. 1992;11:1165–1176
- . Variant chromatin structure of the oriP region of Epstein–Barr virus and regulation of EBER1 expression by upstream sequences and oriP. J. Virol. 2001;75:6235–6241
- . Sequences adjacent to oriP improve the persistence of Epstein–Barr virus-based episomes in B cells. J. Virol. 2001;75:11249–11252
- . Sequence analysis of the 17, 166 base-pair EcoRI fragment C of B95-8 Epstein–Barr virus. Mol. Biol. Med. 1983;1:21–45
- . The EB virus genome in Daudi Burkitt’s lymphoma cells has a deletion similar to that observed in a non-transforming strain (P3HR-1) of the virus. EMBO J. 1984;3:813–821
- . Marked variation in the size of genomic plasmids among members of a family of related Epstein–Barr viruses. Proc. Natl. Acad. Sci. USA. 1992;89:7772–7776
- . Linear association between cellular DNA and Epstein–Barr virus DNA in a human lymphoblastoid cell line. Proc. Natl. Acad. Sci. USA. 1973;70:2888–2892
- . Intracellular forms of Epstein–Barr virus DNA in human tumour cells in vivo. Nature. 1976;260:302–306
- . Epstein–Barr virus integration in human lymphomas and lymphoid cell lines. Cancer. 1992;70:185–191
- . Episomal and integrated copies of Epstein–Barr virus coexist in Burkitt lymphoma cell lines. J. Virol. 1993;67:1292–1299
- . Integration of Epstein Barr virus near the breakpoint of a translocation 11; 19 in a Burkitt’s lymphoma cell line. Cancer Genet. Cytogenet. 1993;67:90–94
- . Selective loss of integrated Epstein–Barr virus genomes after long-term cultivation of Burkitt’s lymphoma
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B-lymphoblastoid cell hybrids due to chromatin instability at the integration site. Virology. 1995;212:179–185 - . Integration of Epstein–Barr virus in Burkitt’s lymphoma cells leads to a region of enhanced chromosome instability. Ann. Oncol. 1997;8(Suppl. 2):131–135
- . Isolation of Epstein–Barr virus (EBV)-negative cell clones from the EBV-positive Burkitt’s lymphoma (BL) line Akata: malignant phenotypes of BL cells are dependent on EBV. J. Virol. 1994;68:6069–6073
- . Spontaneous loss of viral episomes accompanying Epstein–Barr virus reactivation in a Burkitt’s lymphoma cell line. J. Infect. Dis. 1998;177:1705–1709
- . Epstein–Barr virus DNA recombination and loss in sporadic Burkitt’s lymphoma. J. Infect. Dis. 1996;173:529–535
- . Parallel existence of Epstein–Barr virus (EBV) positive and negative cells in a sporadic case of Burkitt lymphoma. Oncogene. 1995;11:505–510
- . The in vivo binding site for oncoprotein c-Myc in the promoter for Epstein–Barr virus (EBV) encoding RNA (EBER) 1 suggests a specific role for EBV in lymphoma genesis. Med. Sci. Monit. 2003;9:HY1–HY9
- . EBV-associated neoplasms: alternative pathogenetic pathways. Med. Hypotheses. 2004;62:387–391
- . The LCR of EBV makes Burkitt’s lymphoma endemic. Trends Microbiol. 2004;12:495–499
- . Dynamic chromatin boundaries delineate a latency control region of Epstein–Barr virus. J. Virol. 2004;78:12308–12319
- . Chromatin profiling of Epstein–Barr virus latency control region. J. Virol. 2007;81:6389–6401
- . Binding of CCCTC-binding factor in vivo to the region located between Rep∗ and C-promoter of Epstein–Barr virus is unaffected by CpG methylation and does not correlate with Cp activity. J. Gen. Virol. 2009;
- . Epstein–Barr virus as a marker of survival after Hodgkin’s lymphoma: a population-based study. J. Clin. Oncol. 2005;23:7604–7613
- . Hodgkin’s disease in patients with previous infectious mononucleosis. Int. J. Cancer. 1979;23:593–597
- . Characteristics of Hodgkin’s lymphoma after infectious mononucleosis. New Engl. J. Med. 2003;349:1324–1332
- . Epstein–Barr virus in Hodgkin’s disease and site of origin of tumour. Lancet. 1994;343:265–266
- . Epstein–Barr virus fatal infectious mononucleosis, and Hodgkin’s disease in siblings. Cancer. 1983;51:509–520
- . Infectious mononucleosis, childhood social environment, and risk of Hodgkin lymphoma. Cancer Res. 2007;67:2382–2388
- . EBV promotes human CD8 NKT cell development. PLoS Pathog. 2010;20(6):e1000915
- . Hodgkin lymphoma and immunodeficiency in persons with HIV/AIDS. Blood. 2006;108:3786–3791
- . Association with HLA class I in Epstein–Barr-virus-positive and with HLA class III in Epstein–Barr-virus-negative Hodgkin’s lymphoma. Lancet. 2005;365:2216–2224
- . HLA-A∗02 is associated with a reduced risk and HLA-A∗01 with an increased risk of developing EBV + Hodgkin lymphoma. Blood. 2007;110:3310–3315
- . HLA class I polymorphisms are associated with development of infectious mononucleosis upon primary EBV infection. J. Clin. Invest. 2007;117:3042–3048
- . Epstein–Barr virus-associated Hodgkin’s disease: epidemiologic characteristics in international data. Int. J. Cancer. 1997;70:375–382
- . An epidemiologic study of index and family infectious mononucleosis and adult Hodgkin’s disease (HD): evidence for a specific association with EBV+ve HD in young adults. Int. J. Cancer. 2003;107:298–302
- . Disappearance of the Epstein–Barr virus in a relapse of Hodgkin’s disease. J. Pathol. 1997;182:475–479
- . Persistence of the same viral strain in early and late relapses of Epstein–Barr virus-associated Hodgkin’s disease. Blood. 1994;84:2447–2451
- . Discrepancies in Epstein–Barr virus association at presentation and relapse of classical Hodgkin’s disease: impact on pathogenesis. Ann. Oncol. 2000;11:475–478
- . Detection of Epstein–Barr virus in Hodgkin–Reed–Sternberg cells: no evidence for the persistence of integrated viral fragments inLatent membrane protein-1 (LMP-1)-negative classical Hodgkin’s disease. Am. J. Pathol. 2000;156:209–216
- . Hodgkin lymphoma and Epstein–Barr virus (EBV): No evidence to support hit-and-run mechanism in cases classified as non-EBV-associated. Int. J. Cancer. 2003;104:624–630
- . Increased incidence of Hodgkin’s disease after allogeneic bone marrow transplantation. J. Clin. Oncol. 1999;17:3122–3127
- . A defective rearranged Epstein–Barr virus genome in EBER-negative and EBER-positive Hodgkin’s disease. Am. J. Pathol. 2002;160:781–786
- . Breast cancer and microbial cancer incidence in female populations around the world: a surprising hyperbolic association. Int. J. Cancer. 2008;123:1094–1099
- . Epidemiology of hodgkin’s disease in the young. Int. J. Cancer. 1977;19:595–604
- . Is breast cancer caused by late exposure to a common virus?. Med. Hypotheses. 1997;48:491–497
- . Observation of cells resembling Sternberg–Reed cells in conditions other than Hodgkin’s disease. Cancer. 1970;26:176–190
- . Breast cancer risk and “delayed” primary Epstein–Barr virus infection. Cancer Epidemiol. Biomarkers Prev. 2001;10:9–16
- . Epstein–Barr virus and breast cancer: state of the evidence for viral carcinogenesis. Cancer Epidemiol. Biomarkers Prev. 2004;13:688–697
- . Epstein–Barr virus in epithelial cell tumors: a breast cancer study. Cancer Res. 1995;55:39–45
- . Epstein–Barr virus (EBV) genome and expression in breast cancer tissue: effect of EBV infection of breast cancer cells on resistance to paclitaxel (Taxol). J. Virol. 2006;80:845–853
- . Lytic viral replication as a contributor to the detection of Epstein–Barr virus in breast cancer. J. Virol. 2003;77:13267–13274
- . Detection of Epstein–Barr virus in invasive breast cancers. J. Natl. Cancer Inst. 1999;91:1376–1381
- . Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation. Lancet. 1995;346:796–798
- . EB viral genomes in epithelial nasopharyngeal carcinoma cells. Nat. New Biol. 1973;244:245–247
- . Nasopharyngeal carcinoma. X. Presence of Epstein–Barr genomes in separated epithelial cells of tumours in patients from Singapore, Tunisia and Kenya. Int. J. Cancer. 1975;16:7–15
- . Seroepidemiological studies on nasopharyngeal carcinoma in China. Adv. Cancer Res. 1985;44:121–138
- . EB virus, nasopharyngeal carcinoma,. In: Zeng Y, Ou B editor. Etiology and Pathogenesis of Nasopharyngeal Carcinoma. Beijing: The People’s Medical Publishing House; 1987;p. 18
- . Focus on nasopharyngeal carcinoma. Cancer Cell. 2004;5:423–428
- . Epstein–Barr virus carriage by nasopharyngeal carcinoma in situ. Int. J. Cancer. 1993;53:746–750
- . Analysis of Epstein–Barr virus infection in nasopharyngeal biopsies from a group at high risk of nasopharyngeal carcinoma. Int. J. Cancer. 1993;53:957–962
- . Clonal proliferations of cells infected with Epstein–Barr virus in preinvasive lesions related to nasopharyngeal carcinoma. New Engl. J. Med. 1995;333:693–698
- . Nasopharyngeal carcinoma in situ (NPCIS) – pathologic and clinical perspectives. Head Neck. 2002;24:989–995
- . Nasopharyngeal intraepithelial lesion: latent Epstein–Barr virus infection with malignant potential. Histopathology. 2004;45:171–179
- . Epstein–Barr virus in the pathogenesis of NPC. Semin. Cancer Biol. 2002;12:431–441
- . Virus target cell conditioning model to explain some epidemiologic characteristics of childhood leukemias and lymphomas. Int. J. Cancer. 2005;115:1–5
- . Functional delivery of viral miRNAs via exosomes. Proc. Natl. Acad. Sci. USA. 2010;107:6328–6333
- . Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein–Barr virus. Int. J. Cancer. 1999;83:121–126
- . Multiple pathways for Epstein–Barr virus episome loss from nasopharyngeal carcinoma. Int. J. Cancer. 2008;123:2105–2112
- . Epstein–Barr virus infection to Epstein–Barr virus-negative nasopharyngeal carcinoma cell line TW03 enhances its tumorigenicity. Lab. Invest. 2000;80:303–312
- . Identification of integrated Epstein–Barr virus in nasopharyngeal carcinoma using pulse field gel electrophoresis. Int. J. Cancer. 1994;56:187–192
- . EBV gene expression in an NPC-related tumour. EMBO J. 1989;8:2639–2651
- . Epstein–Barr virus complementary strand transcripts (CSTs/BARTs) and cancer. Semin. Cancer Biol. 2001;11:469–476
- . Establishment of immortalized primate epithelial cells with sub-genomic EBV DNA. Int. J. Cancer. 1990;45:763–772
- . Epstein–Barr virus gene expression in human breast cancer: protagonist or passenger?. Br. J. Cancer. 2003;89:113–119
- . Hypothesis: a novel route for immortalization of epithelial cells by Epstein–Barr virus. Oncogene. 2002;21:825–835
- . Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein–Barr virus-transformed human B lymphocytes. J. Virol. 1994;68:3410–3414
- . Demonstration of the Burkitt’s lymphoma Epstein–Barr virus phenotype in dividing latently infected memory cells in vivo. Proc. Natl. Acad. Sci. USA. 2004;101:239–244
- . Peripheral B cells latently infected with Epstein–Barr virus display molecular hallmarks of classical antigen-selected memory B cells. Proc. Natl. Acad. Sci. USA. 2005;102:18093–18098
- . A 30 kb region of the Epstein–Barr virus genome is colinear with the rearranged human immunoglobulin gene loci: implications for a “ping-pong evolution” model for persisting viruses and their hosts. A review. Acta Microbiol. Immunol. Hung. 2004;51:469–484
- . Expression of interleukin-10 activity by Epstein–Barr virus protein BCRF1. Science. 1990;250:830–832
- . Epstein–Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor. EMBO J. 1998;17:1700–1709
- . Epstein–Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. Immunity. 1998;9:405–411
- . Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease. Proc. Natl. Acad. Sci. USA. 1998;95:2463–2468
- . LR1 regulates c-myc transcription in B-cell lymphomas. Proc. Natl. Acad. Sci. USA. 1994;91:4915–4919
- . Autoantigenic proteins that bind recombinogenic sequences in Epstein–Barr virus and cellular DNA. Proc. Natl. Acad. Sci. USA. 1994;91:8646–8650
- . Activation and targeting of immunoglobulin switch recombination by activities induced by EBV infection. J. Immunol. 1999;163:6659–6664
- . Deletion of the nontransforming Epstein–Barr virus strain P3HR-1 causes fusion of the large internal repeat to the DSL region. J. Virol. 1982;43:952–968
- . Non-immortalizing P3J-HR-1 Epstein–Barr virus: a deletion mutant of its transforming parent, Jijoye. J. Virol. 1982;44:834–844
- . Thymic carcinoma with a defective Epstein–Barr virus encoding the BZLF1 trans-activator. J. Infect. Dis. 1994;170:7–12
- . Infection of human B cells with Epstein–Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations. Mol. Immunol. 2007;44:934–942
- . Analysis of VH genes used by neoplastic B cells in endemic Burkitt’s lymphoma shows somatic hypermutation and intraclonal heterogeneity. Blood. 1995;85:2176–2181
- . Burkitt’s lymphomas express VH genes with a moderate number of antigen-selected somatic mutations. Am. J. Pathol. 1995;147:1398–1407
- . Epstein–Barr virus and the somatic hypermutation of immunoglobulin genes in Burkitt’s lymphoma cells. J. Virol. 2001;75:10488–10492
- . Enhancement of genetic instability in human B cells by Epstein–Barr virus latent infection. Mutagenesis. 2001;16:203–208
- . Epstein–Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells. Oncogene. 2004;23:2531–2539
- . Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature. 2006;440:105–109
- . EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching. J. Immunol. 2003;171:5215–5224
- . Epstein–Barr virus nuclear antigen 2 inhibits AID expression during EBV-driven B-cell growth. Blood. 2006;108:3859–3864
- . Frequent expansion of Epstein–Barr virus (EBV) infected cells in germinal centres of tonsils from an area with a high incidence of EBV-associated lymphoma. J. Pathol. 1999;187:326–330
- . Epstein–Barr virus-infected B cells expanding in germinal centers of infectious mononucleosis patients do not participate in the germinal center reaction. Proc. Natl. Acad. Sci. USA. 2003;100:4730–4735
- . The intersection of Epstein–Barr virus with the germinal center. J. Virol. 2009;83:3968–3976
- . Germinal center B cells latently infected with Epstein–Barr virus proliferate extensively but do not increase in number. J. Virol. 2010;84:1158–1168
- . Mimicry of CD40 signals by Epstein–Barr virus LMP1 in B lymphocyte responses. Science. 1999;286:300–303
- . Epstein–Barr virus induction of recombinase-activating genes RAG1 and RAG2. J. Virol. 1995;69:8155–8158
- . Bcl-xL and RAG genes are induced and the response to IL-2 enhanced in EmuEBNA-1 transgenic mouse lymphocytes. Oncogene. 2002;21:5182–5187
- . Expression of recombination activating genes (RAG-1 and RAG-2) in Epstein–Barr virus-bearing B cells. Blood. 1995;85:1289–1299
- . Peripheral blood lymphocytes express recombination-activating genes 1 and 2 during Epstein–Barr virus-induced infectious mononucleosis. J. Infect. Dis. 2004;190:979–984
- . The DDE recombinases: diverse roles in acquired and innate immunity. Ann. Allergy Asthma Immunol. 2006;97:567–576
- . Paleo-immunology: evidence consistent with insertion of a primordial herpes virus-like element in the origins of acquired immunity. PLoS ONE. 2009;4:e5778
- . Expression of the recombination activating genes (RAG1 and RAG2) is not detectable in Epstein–Barr virus-associated human lymphomas. Int. J. Cancer. 2001;92:75–78
- . Expression of the recombination-activating genes in extrafollicular lymphocytes but no apparent reinduction in germinal center reactions in human tonsils. Blood. 2002;99:531–537
- . Concatameric replication of Epstein–Barr virus: structure of the termini in virus-producer and newly transformed cell lines. J. Virol. 1990;64:5295–5300
- . Sp1 binds to the precise locus of end processing within the terminal repeats of Epstein–Barr virus DNA. J. Virol. 1997;71:6136–6143
- . Homologous recombinational repair factors are recruited and loaded onto the viral DNA genome in Epstein–Barr virus replication compartments. J. Virol. 2009;83:6641–6651
- . Oncogenesis in Ataxia Telangectasia: roles of ATM, p53, NF-kB and DDE recombination pathogenesis. In: Ahmad SI editors. Molecular Mechanisms of Ataxia Teleangiectasia. Austin: Landes Bioscience; 2009;p. 78–90
- . Expression of heavy-chain constant region of immunoglobulin and T-cell receptor gene transcripts in human non-hematopoietic tumor cell lines. Genes Chromosomes Cancer. 1998;22:83–86
- . Illegitimate transcription: transcription of any gene in any cell type. Proc. Natl. Acad. Sci. USA. 1989;86:2617–2621
- . Human epithelial cancers secrete immunoglobulin g with unidentified specificity to promote growth and survival of tumor cells. Cancer Res. 2003;63:6488–6495
- . Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines. Genes Chromosomes Cancer. 2005;42:58–67
- . Immunoglobulin G expression in carcinomas and cancer cell lines. FASEB J. 2007;21:2931–2938
- . Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines. Cancer Res. 2006;66:3996–4000
- . Upregulated expression of kappa light chain by Epstein–Barr virus encoded latent membrane protein 1 in nasopharyngeal carcinoma cells via NF-kappaB and AP-1 pathways. Cell Signal. 2007;19:419–427
- . Translating the histone code. Science. 2001;293:1074–1080
- . DNA methylation patterns and epigenetic memory. Genes Dev. 2002;16:6–21
- . The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J. Biol. Chem. 2003;278:4035–4040
- . Epigenome programming by Polycomb and Trithorax proteins. Biochem. Cell Biol. 2005;83:322–331
- . The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. Development. 2008;135:1935–1946
- . Epigenetic field for cancerization. J. Biochem. Mol. Biol. 2007;40:142–150
- . DNA hypomethylation and cancer. In: Ehrlich M editors. DNA Alterations in Cancer. Westborough: Eaton Publishing; 2000;p. 273–291
- . Excavating relics of DNA methylation changes during the development of neoplasia. Semin. Cancer Biol. 2009;19:198–208
- . Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Res. 2004;64:8184–8192
- . High-density methylation of p14ARF and p16INK4A in Epstein–Barr virus-associated gastric carcinoma. Int. J. Cancer. 2004;112:273–278
- . P73 gene promoter methylation in Epstein–Barr virus-associated gastric carcinoma. Int. J. Cancer. 2007;120:60–66
- . DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis. Lab. Invest. 2008;88:161–170
- . ATP-dependent mobilization of the glucocorticoid receptor during chromatin remodeling. Mol. Cell Biol. 2002;22:3255–3263
- . Subnuclear trafficking and gene targeting by steroid receptors. Ann. NY Acad. Sci. 2004;1024:213–220
- . Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Mol. Cell. 2008;31:909–917
- . Expression of DNA methyltransferase 1 is activated by hepatitis B virus X protein via a regulatory circuit involving the p16INK4a-cyclin D1-CDK 4/6-pRb-E2F1 pathway. Cancer Res. 2007;67:5771–5778
- . Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Gastroenterology. 2007;132:1476–1494
- . Isolation of NotI clusters hypomethylated in HBV-integrated hepatocellular carcinomas by two-dimensional electrophoresis. DNA Res. 1999;6:219–225
- . Hepatitis C virus core protein downregulates E-cadherin expression via activation of DNA methyltransferase 1 and 3b. Cancer Lett. 2008;261:244–252
- . Epigenetic silencing of interferon-inducible genes is implicated in interferon resistance of hepatitis C virus replicon-harboring cells. J. Hepatol. 2006;44:869–878
- . Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma. Am. J. Pathol. 2003;163:1101–1107
- . P16INK4A hypermethylation is associated with hepatitis virus infection, age, and gender in hepatocellular carcinoma. Clin. Cancer Res. 2004;10:7484–7489
- . P16 promoter hypermethylation in human hepatocellular carcinoma with or without hepatitis virus infection. Intervirology. 2004;47:26–31
- . Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins. Carcinogenesis. 2003;24:159–169
- . Life and death decisions by the E2F transcription factors. Curr. Opin. Cell Biol. 2007;19:649–657
- . Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway. Cancer Res. 2005;65:3624–3632
- . Human polyomavirus BKV transcriptionally activates DNA methyltransferase 1 through the pRb/E2F pathway. Oncogene. 2006;25:2727–2735
- . Viral oncoproteins target the DNA methyltransferases. Oncogene. 2007;26:1650–1655
- . Chromatin at the intersection of viral infection and DNA damage. Biochim. Biophys. Acta. 2009;1:1–10(epub ahead of print)
- . Chromosomal insertion of foreign (adenovirus type 12, plasmid, or bacteriophage lambda) DNA is associated with enhanced methylation of cellular DNA segments. Proc. Natl. Acad. Sci. USA. 1995;92:5515–5519
- . Epigenetic mechanisms in human adenovirus type 12 oncogenesis. Semin. Cancer Biol. 2009;19:136–143
- . Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen. Science. 1996;273:1384–1386
- . Studying development of disease through temporally controlled gene expression in the salivary gland. Ann. NY Acad. Sci. 1998;842:181–187
- . Stabilization of DNA methyltransferase levels and CpG island hypermethylation precede SV40-induced immortalization of human fibroblasts. Cell Growth Differ. 1994;5:1395–1402
- . DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras. Oncogene. 2003;22:4723–4733
- . Epigenetic regulation of Kaposi’s sarcoma-associated herpesvirus replication. Semin. Cancer Biol. 2009;19:153–157
- . The Epstein–Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc. Natl. Acad. Sci. USA. 2002;99:10084–10089
- . Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signaling. Cancer Res. 2006;66:11668–11676
- . Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi’s sarcoma-associated herpesvirus LANA. Proc. Natl. Acad. Sci. USA. 2006;103:14554–14559
- . KSHV LANA inhibits TGF-beta signaling through epigenetic silencing of the TGF-beta type II receptor. Blood. 2008;111:4731–4740
- . The HTLV-1 tax interactome. Retrovirology. 2008;5(76):76
- . The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplication. Nat. Cell Biol. 2006;8:717–724
- . DNA aneuploidy of adult T-cell leukemia cells. Leuk. Res. 1994;18:79–84
- . Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL). Retrovirology. 2005;2(27):1–13
- . Mechanisms of SHP-1 P2 promoter regulation in hematopoietic cells and its silencing in HTLV-1-transformed T cells. J. Leukocyte Biol. 2009;85:165–174
PII: S0304-3835(10)00388-5
doi: 10.1016/j.canlet.2010.08.007
© 2010 Elsevier Ireland Ltd. All rights reserved.
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Cancer Letters
Volume 305, Issue 2
, Pages 200-217
, 28 June 2011
