Cancer Letters
Volume 299, Issue 1 , Pages 22-28, 18 December 2010

RAD001 shows activity against gastric cancer cells and overcomes 5-FU resistance by downregulating thymidylate synthase

  • Kyung-Hun Lee

      Affiliations

    • Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
    • These authors equally contributed to this work as first authors.
    • ,
  • Hyung-Seok Hur

      Affiliations

    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • These authors equally contributed to this work as first authors.
    • ,
  • Seock-Ah Im

      Affiliations

    • Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • Corresponding Author InformationCorresponding author at: Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehang-ro, Jongno-gu, Seoul, 110-744, Republic of Korea. Tel.: +82 2 2072 0850; fax: +82 2 762 9662.
    • ,
  • Juhee Lee

      Affiliations

    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • ,
  • Hwang-Phill Kim

      Affiliations

    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • ,
  • Young-Kwang Yoon

      Affiliations

    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • ,
  • Sae-Won Han

      Affiliations

    • Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • ,
  • Sang-Hyun Song

      Affiliations

    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • ,
  • Do-Youn Oh

      Affiliations

    • Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • ,
  • Tae-You Kim

      Affiliations

    • Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine or College of Pharmacy, Seoul National University, Republic of Korea
    • ,
  • Yung-Jue Bang

      Affiliations

    • Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea
    • Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
    • Corresponding Author InformationCorresponding author at: Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehang-ro, Jongno-gu, Seoul, 110-744, Republic of Korea. Tel.: +82 2 2072 2390; fax: +82 2 762 9662.

Received 19 February 2010; received in revised form 22 June 2010; accepted 22 July 2010. published online 20 August 2010.

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PII: S0304-3835(10)00379-4

doi:10.1016/j.canlet.2010.07.020

Cancer Letters
Volume 299, Issue 1 , Pages 22-28, 18 December 2010

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