Cancer Letters
Volume 298, Issue 2 , Pages 238-249 , 8 December 2010

Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cells

  • Joo Hyoung Lee

      Affiliations

    • Department of Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, AL 35294-4400, United States
    • Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham, Birmingham, AL 35294-4400, United States
    • ,
  • Lakisha D. Moore

      Affiliations

    • Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294-4400, United States
    • ,
  • Sanjay Kumar

      Affiliations

    • Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294-4400, United States
    • ,
  • David G. Pritchard

      Affiliations

    • Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294-4400, United States
    • ,
  • Selvarangan Ponnazhagan

      Affiliations

    • Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294-4400, United States
    • ,
  • Champion Deivanayagam

      Affiliations

    • Department of Vision Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-4400, United States
    • Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham, Birmingham, AL 35294-4400, United States
    • Corresponding Author InformationCorresponding author. Address: Department of Vision Sciences, Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham, 1025 18th Street South, CBSE 100, Birmingham, AL 35294-4400, United States. Tel.: +1 205 934 6026; fax: +1 205 934 0480.

Received 7 April 2010 ,Revised 8 July 2010 ,Accepted 12 July 2010.

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PII: S0304-3835(10)00359-9

doi: 10.1016/j.canlet.2010.07.011

Cancer Letters
Volume 298, Issue 2 , Pages 238-249 , 8 December 2010

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