In vivo antitumor and antimetastatic activities of camptothecin encapsulated with N-trimethyl chitosan in a preclinical mouse model of liver cancer

Zhou, Lina; Li, Xingyi; Chen, Xiancheng; Li, Zhiyong; Liu, Xianping; Zhou, Shengtao; Zhong, Qian; Yi, Tao; Wei, Yuquan; Zhao, Xia; Qian, Zhiyong

doi:10.1016/j.canlet.2010.04.024

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Volume 297, Issue 1 , Pages 56-64, 1 November 2010

In vivo antitumor and antimetastatic activities of camptothecin encapsulated with N-trimethyl chitosan in a preclinical mouse model of liver cancer

Lina Zhou
- Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
Xingyi Li
- State Key Laboratory, Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
Xiancheng Chen
- State Key Laboratory, Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
Zhiyong Li
- State Key Laboratory, Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
Xianping Liu
- Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
Shengtao Zhou
- Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
Qian Zhong
- Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
Tao Yi
- Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
Yuquan Wei
- State Key Laboratory, Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
Xia Zhao
- Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
- Correspondence to: Xia Zhao, Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, No. 20, Section 3, South People’s Road, Chengdu 610041, Sichuan, People’s Republic of China. Tel./fax: +86 28 85501633.
Zhiyong Qian
- State Key Laboratory, Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, People’s Republic of China
- Correspondence to: Zhiyong Qian, State Key Laboratory, Biotherapy and Cancer Center, West China Hospital, Sichuan University, Keyuan Road 4 No. 1, Gaopeng Street, High Technological Development Zone, Chengdu 610041, Sichuan, People’s Republic of China. Tel.: +86 28 85164063; fax: +86 28 85164060.