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Cancer Letters
Volume 297, Issue 1
, Pages 49-55
, 1 November 2010
Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma
References
- . Cancer statistics. CA Cancer J. Clin. 2009;59:225–249
- . TRP channels as potential drug targets. Biol. Cell. 2004;96:47–54
- . TRP channels in cancer. Biochim. Biophys. Acta. 2007;1772:937–946
- . TRP channels as cellular sensors. Nature. 2003;426:517–523
- . TRP channels. Annu. Rev. Biochem. 2007;76:387–417
- . Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis. Cancer Res. 1998;58:1515–1520
- . Cell death of melanophores in zebrafish trpm7 mutant embryos depends on melanin synthesis. J. Invest. Dermatol. 2007;127:2020–2030
- . Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression. Human Mol. Genet. 2000;9:203–216
- . TRPM7, a novel regulator of actomyosin contractility and cell adhesion. EMBO J. 2006;25:290–301
- . Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. Cancer Res. 2007;67:10929–10938
- . Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer. Cancer Sci. 2008;99:2502–2509
- . Evidence that TRPM7 is required for breast cancer cell proliferation. Am. J. Physiol. Cell Physiol. 2009;297:C493–C502
- . Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. Cancer Res. 2001;61:3760–3769
- . Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells. Cancer Res. 2004;64:8365–8373
- . Transient receptor potential channel TRPM8 agonists stimulate calcium influx and neurotensin secretion in neuroendocrine tumor cells. Neuroendocrinology. 2007;85:81–92
- . Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16. Am. J. Pathol. 1996;148:1763–1770
- . Combined targeting of histone deacetylases and hedgehog signaling enhances cytotoxicity in pancreatic cancer. Cancer Biol. Ther. 2009;8:1328–1339
- . Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature. 2002;416:52–58
- . A TRP channel that senses cold stimuli and menthol. Cell. 2002;108:705–715
- . Pathways of apoptotic and non-apoptotic death in tumour cells. Nat. Rev. Cancer. 2004;4:592–603
- . Tissue distribution profiles of the human TRPM cation channel family. J. Recept. Signal Transduc. 2006;26:159–178
- . Evidence for specific TRPM8 expression in human prostate secretory epithelial cells: functional androgen receptor requirement. Endocr. Relat. Cancer. 2005;12:367–382
- . Novel role of cold/menthol-sensitive transient potential melastatin family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells. J. Biol. Chem. 2005;280:39423–39435
- . Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function. J. Clin. Invest. 2007;117:1647–1657
- . Androgen receptor blockade in experimental combination therapy of pancreatic cancer. J. Surg. Res. 2007;142:378–386
- . Vanilloids in pancreatic cancer: potential for chemotherapy and pain management. Gut. 2006;55:519–528
PII: S0304-3835(10)00238-7
doi: 10.1016/j.canlet.2010.04.023
© 2010 Elsevier Ireland Ltd. All rights reserved.
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Cancer Letters
Volume 297, Issue 1
, Pages 49-55
, 1 November 2010
