Cancer Letters
Volume 297, Issue 1 , Pages 18-30 , 1 November 2010

A novel compound modified from tanshinone inhibits tumor growth in vivo via activation of the intrinsic apoptotic pathway

  • Hong-Lei Tian

      Affiliations

    • Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
    • ,
  • Ting Yu

      Affiliations

    • Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637457, Singapore
    • ,
  • Nai-Ning Xu

      Affiliations

    • Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
    • ,
  • Chao Feng

      Affiliations

    • Department of Chemical and Biomolecular Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
    • ,
  • Li-Ying Zhou

      Affiliations

    • Department of Chemical and Biomolecular Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
    • ,
  • Hou-Wei Luo

      Affiliations

    • Department of Natural Medical Chemistry, China Pharmaceutical University, Nanjing, China
    • ,
  • Donald C. Chang

      Affiliations

    • Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
    • ,
  • Xiao-Feng Le

      Affiliations

    • Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
    • ,
  • Kathy Qian Luo

      Affiliations

    • Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637457, Singapore
    • Corresponding Author InformationCorresponding author. Address: Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, Singapore 637457, Singapore. Tel.: +65 6790 4257; fax: +65 6791 1761.

Received 30 December 2009 ,Revised 12 April 2010 ,Accepted 22 April 2010.

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PII: S0304-3835(10)00235-1

doi: 10.1016/j.canlet.2010.04.020

Cancer Letters
Volume 297, Issue 1 , Pages 18-30 , 1 November 2010

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