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Cancer Letters
Volume 295, Issue 1
, Pages 110-123
, 1 September 2010
Autocrine production of interleukin-6 confers cisplatin and paclitaxel resistance in ovarian cancer cells
References
- . Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat. Rev. Cancer. 2003;3:502–516
- . Drug resistance in ovarian cancer: the emerging importance of gene transcription and spatio-temporal regulation of resistance. Drug Resist. Updates. 2005;8:311–321
- . Interleukin-6-type cytokines. Ann. NY. Acad. Sci. 1995;762:1–14
- . Interleukin-6 and its receptor in cancer: implications for translational therapeutics. Cancer. 2007;110:1911–1928
- . Interleukin-6 prevents dexamethasone-induced myeloma cell death. Blood. 1994;84:3063–3070
- . Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells. Blood. 1997;89:227–234
- . Sensitization of human renal cell carcinoma cells to cis-diamminedichloroplatinum (II) by anti-interleukin 6 monoclonal antibody or anti-interleukin 6 receptor monoclonal antibody. Cancer Res. 1995;55:590–596
- . Cholangiocarcinoma: current concepts and insights. Hepatology. 2003;37:961–969
- . Endogenous interleukin 6 is a resistance factor for cis-diamminedichloroplatinum and etoposide-mediated cytotoxicity of human prostate carcinoma cell lines. Cancer Res. 1995;55:4633–4639
- . Prostate cancer cells (LNCaP) generated after long-term interleukin 6 (IL-6) treatment express IL-6 and acquire an IL-6 partially resistant phenotype. Clin. Cancer Res. 2001;7:2941–2948
- . Interleukin-6 is responsible for drug resistance and anti-apoptotic effects in prostatic cancer cells. Prostate. 2004;60:120–129
- . Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells. Cancer Res. 2001;61:8851–8858
- . Interleukin-6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer. Cancer. 1994;73:1882–1888
- . Interleukin-6 serum levels in patients with gynecological tumors. Int. J. Cancer. 1994;57:318–323
- . Serum evaluation of interleukin 6 in ovarian cancer patients. Gynecol. Oncol. 1997;66:27–30
- . Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer. Brit. J. Cancer. 1995;71:354–356
- . Cytokines IL-1beta, IL-2, IL-6, IL-8, MCP-1, GM-CSF and TNFalpha in patients with epithelial ovarian cancer and their relationship to treatment with paclitaxel. Int. J. Gynecol. Cancer. 2000;10:33–41
- . Effects of interleukin-6 on in vitro cell attachment, migration and invasion of human ovarian carcinoma. Anticancer Res. 1997;17:337–342
- . Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine. Cancer Res. 2005;65:10794–10800
- . Regulation of ovarian carcinoma SKOV-3 cell proliferation and secretion of MMPs by autocrine IL-6. Anticancer Res. 2007;27:267–272
- . Reciprocal regulation of 5alpha-dihydrotestosterone, interleukin-6 and interleukin-8 during proliferation of epithelial ovarian carcinoma. Cancer Biol. Ther. 2007;6:864–871
- . Reciprocal regulation of 17beta-estradiol, interleukin-6 and interleukin-8 during growth and progression of epithelial ovarian cancer. Cytokine. 2009;46:382–391
- . Discovery of differentially expressed genes associated with paclitaxel resistance using cDNA array technology: analysis of interleukin (IL) 6, IL-8, and monocyte chemotactic protein 1 in the paclitaxel-resistant phenotype. Clin. Cancer Res. 1999;5:3445–3453
- . Signaling mechanisms through gp130: a model of the cytokine system. Cytokine Growth Factor Rev. 1997;8:241–252
- . Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line. J. Biol. Chem. 1999;274:31648–31654
- . Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin. Clin. Cancer Res. 1999;5:1007–1014
- . A high nuclear basal level of ERK2 phosphorylation contributes to the resistance of cisplatin-resistant human ovarian cancer cells. Gynecol. Oncol. 2007;104:338–344
- . Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin. Cancer Res. 2000;60:5988–5994
- . Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel. J. Biol. Chem. 2002;277:33490–33500
- . Inhibition of phosphatidylinositol 3-kinase increases efficacy of cisplatin in in vivo ovarian cancer models. Endocrinology. 2006;147:1761–1769
- . Inhibition of phosphatidylinositol 3-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models. Cancer Res. 2002;62:1087–1092
- . The control of apoptosis and drug resistance in ovarian cancer: influence of p53 and bcl-2. Oncogene. 1995;11:1217–1228
- . Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease. Gynecol. Oncol. 2005;96:287–295
- . Human ovarian cancer and cisplatin resistance. possible role of inhibitor of apoptosis proteins. Endocrinology. 2001;142:370–380
- . Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells. Cancer Res. 2000;60:5659–5666
- . Reproductive hormone-induced, STAT3-mediated interleukin 6 action in normal and malignant human ovarian surface epithelial cells. J. Natl. Cancer Inst. 2002;94:617–629
- . Inhibition of extracellular signal regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line. J. Biol. Chem. 1999;274:31648–31654
- . Regulation of spontaneous and TNF/IFN-induced IL-6 expression in two human ovarian-carcinoma cell lines. Int. J. Cancer. 1999;82:244–249
- . Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells. Cytokine. 2002;17:234–242
- . P-glycoprotein expression is a marker for chemotherapy resistance and prognosis in advanced ovarian cancer. Anticancer Res. 2000;20:1061–1067
- . Evaluation of chemoresistance markers in women with epithelial ovarian carcinoma. Gynecol. Oncol. 2001;81:18–24
- . Multidrug resistance-related phenotype and apoptosis-related protein expression in ovarian serous carcinomas. Gynecol. Oncol. 2006;100:152–159
- . Heterogeneity of glutathione S-transferase enzyme and gene expression in ovarian carcinoma. Pharmacogenetics. 1992;2:63–72
- . Glutathione-dependent enzymes in ovarian adenocarcinoma cell lines derived from a patient before and after the onset of drug resistance. intrinsic differences and cell cycle effects. Carcinogenesis. 1998;9:1283–1287
- . Modulation of cisplatin cytotoxicity by sulphasalazine. Brit. J. Cancer. 1994;70:190–194
- . Reversal of multidrug resistance by small interfering double-stranded RNAs in ovarian cancer cells. Gynecol. Oncol. 2005;97:501–507
- . Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo. Cancer Res. 1995;55:4438–4445
- . Prevention of myeloma cell apoptosis by ectopic bcl-2 expression or interleukin-6-mediated upregulation of bcl-xL. Cancer Res. 1995;55:2262–2265
- . IL-6 inhibits apoptosis and retains oxidative DNA lesions in human gastric cancer AGS cells through up-regulation of anti-apoptotic gene mcl-1. Carcinogenesis. 2001;22:1947–1953
- . Translational regulation of x-linked inhibitor of apoptosis protein by interleukin-6: a novel mechanism of tumor cell survival. Cancer Res. 2004;64:1293–1298
- . Inhibition of phosphorylation of a forkhead transcription factor sensitizes human ovarian cancer cells to cisplatin. Endocrinology. 2004;145:2014–2022
- . Inhibition of NFkB increases the efficacy of cisplatin in in vitro and in vivo ovarian cancer models. J. Biol. Chem. 2004;279:23477–23485
- . Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer. Clin. Cancer Res. 2006;12:5055–5063
- . STATs and gene regulation. Science. 1997;277:1630–1635
- . Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 2002;3:651–662
- . The STATs of cancer-new molecular targets come of age. Nat. Rev. Cancer. 2004;4:97–105
- . SRC tyrosine kinase and multidrug resistance protein-1inhibitions act independently but cooperatively to restore paclitaxel sensitivity to paclitaxel-resistant ovarian cancer cells. Cancer Res. 2005;65:10381–10388
- . Coexpression of oncostatin M and its receptors and evidence for STAT3 activation in human ovarian carcinomas. Cytokine. 2002;17:324–334
- . Persistent activation of stat3 signaling induces surviving gene expression and confers resistance to apoptosis in human breast cancer cells. Clin. Cancer. Res. 2006;12:11–19
PII: S0304-3835(10)00120-5
doi: 10.1016/j.canlet.2010.02.019
© 2010 Elsevier Ireland Ltd. All rights reserved.
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Cancer Letters
Volume 295, Issue 1
, Pages 110-123
, 1 September 2010
