Cancer Letters
Volume 291, Issue 2 , Pages 225-229 , 28 May 2010

Tuning of apoptosis-mediator gene transcription in HepG2 human hepatoma cells through an adenosine signal

  • Dongqin Yang

      Affiliations

    • Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan
    • ,
  • Takahiro Yaguchi

      Affiliations

    • Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan
    • ,
  • Chun-Ren Lim

      Affiliations

    • DNA Chip Research Inc., 1-1-43 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan
    • ,
  • Youhei Ishizawa

      Affiliations

    • DNA Chip Research Inc., 1-1-43 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan
    • ,
  • Takashi Nakano

      Affiliations

    • Department of Thoracic Oncology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan
    • ,
  • Tomoyuki Nishizaki

      Affiliations

    • Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 798 45 6397; fax: +81 798 45 6649.

Received 14 September 2009 ,Revised 20 October 2009 ,Accepted 20 October 2009.

References 

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  2. Saitoh M, Nagai K, Nakagawa K, Yamamura T, Yamamoto S, Nishizaki T. Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase. Biochem. Pharmacol. 2004;67:2005–2011
  3. Sai K, Yang D, Yamamoto H, Fujikawa H, Yamamoto S, Nagata T, et al. A1 adenosine receptor signal and AMPK involving caspase-9/-3 activation are responsible for adenosine-induced RCR-1 astrocytoma cell death. Neurotoxicology. 2006;27:458–467
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PII: S0304-3835(09)00638-7

doi: 10.1016/j.canlet.2009.10.016

Cancer Letters
Volume 291, Issue 2 , Pages 225-229 , 28 May 2010

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