Cancer Letters
Volume 291, Issue 2 , Pages 200-208, 28 May 2010

Triptolide simultaneously induces reactive oxygen species, inhibits NF-κB activity and sensitizes 5-fluorouracil in colorectal cancer cell lines

  • Bing Xu

      Affiliations

    • Research Institute in Healthcare Science, School of Applied Sciences, University of Wolverhampton, Wolverhampton WV1 1SB, UK
    • Nanfang Hospital, The Southern Medical University, Guangzhou, PR China
    • Visiting fellow from Nanfang Hospital, The Southern Medical University, Guangzhou, PR China.
    • Equally contributed to this work.
    • ,
  • Xiaoxia Guo

      Affiliations

    • Research Institute in Healthcare Science, School of Applied Sciences, University of Wolverhampton, Wolverhampton WV1 1SB, UK
    • Equally contributed to this work.
    • ,
  • Sumi Mathew

      Affiliations

    • Research Institute in Healthcare Science, School of Applied Sciences, University of Wolverhampton, Wolverhampton WV1 1SB, UK
    • ,
  • Angel L Armesilla

      Affiliations

    • Research Institute in Healthcare Science, School of Applied Sciences, University of Wolverhampton, Wolverhampton WV1 1SB, UK
    • ,
  • James Cassidy

      Affiliations

    • Centre for Oncology and Applied Pharmacology, University of Glasgow, Glasgow, UK
    • ,
  • John L Darling

      Affiliations

    • Research Institute in Healthcare Science, School of Applied Sciences, University of Wolverhampton, Wolverhampton WV1 1SB, UK
    • ,
  • Weiguang Wang

      Affiliations

    • Research Institute in Healthcare Science, School of Applied Sciences, University of Wolverhampton, Wolverhampton WV1 1SB, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 1902 322756; fax: +44 1902 322714.

Received 14 August 2009; received in revised form 14 October 2009; accepted 15 October 2009. published online 11 November 2009.

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PII: S0304-3835(09)00635-1

doi:10.1016/j.canlet.2009.10.013

Cancer Letters
Volume 291, Issue 2 , Pages 200-208, 28 May 2010

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