Cancer Letters
Volume 291, Issue 1 , Pages 99-107 , 1 May 2010

Decreased expression of microRNA-199b increases protein levels of SET (protein phosphatase 2A inhibitor) in human choriocarcinoma

  • Angel Chao

      Affiliations

    • Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taiwan
    • Both authors contributed equally to this study.
    • ,
  • Chia-Lung Tsai

      Affiliations

    • Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taiwan
    • Both authors contributed equally to this study.
    • ,
  • Pei-Chi Wei

      Affiliations

    • Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taiwan
    • ,
  • Swei Hsueh

      Affiliations

    • Department of Clinical Pathology, Chang Gung Memorial Hospital and Chang Gung University, Taiwan
    • ,
  • An-Shine Chao

      Affiliations

    • Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taiwan
    • ,
  • Chin-Jung Wang

      Affiliations

    • Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taiwan
    • ,
  • Chi-Neu Tsai

      Affiliations

    • Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taiwan
    • ,
  • Yun-Shien Lee

      Affiliations

    • Department of Biotechnology, Ming-Chuan University, Taiwan
    • Genomic Medicine Research Core Laboratory, Chang Gung Memorial Hospital, Taiwan
    • Corresponding Author InformationCorresponding authors. Address: Genomic Medicine Research Core Laboratory, Chang Gung Memorial Hospital, Taiwan. Tel.: +886 3 3281200; fax: +886 3 3288252 (T.-H. Wang).
    • ,
  • Tzu-Hao Wang

      Affiliations

    • Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taiwan
    • Genomic Medicine Research Core Laboratory, Chang Gung Memorial Hospital, Taiwan
    • Corresponding Author InformationCorresponding authors. Address: Genomic Medicine Research Core Laboratory, Chang Gung Memorial Hospital, Taiwan. Tel.: +886 3 3281200; fax: +886 3 3288252 (T.-H. Wang).
    • ,
  • Chyong-Huey Lai

      Affiliations

    • Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taiwan

Received 1 January 2009 ,Revised 13 May 2009 ,Accepted 9 October 2009.

References 

  1. Soper JT, Creasman WT. Gestational trophoblastic disease. In:  DiSaia PJ,  Creasman WT editor. Clinical Gynecologic Oncology. Mosby, Elsevier; 2007;p. 201–233
  2. Hertz R, Li MC, Spencer DB. Effect of methotrexate therapy upon choriocarinoma and chorioadenoma. Proc. Soc. Exp. Biol. Med. 1956;93:361–366
  3. Shih Ie M. Gestational trophoblastic neoplasia – pathogenesis and potential therapeutic targets. Lancet Oncol. 2007;8:642–650
  4. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281–297
  5. Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. USA. 2002;99:15524–15529
  6. Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H, et al. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 2004;64:3753–3756
  7. Yanaihara N, Caplen N, Bowman E, Seike M, Kumamoto K, Yi M, et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell. 2006;9:189–198
  8. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. USA. 2006;103:2257–2261
  9. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, et al. MicroRNA expression profiles classify human cancers. Nature. 2005;435:834–838
  10. Wang TH, Chan YH, Chen CW, Kung WH, Lee YS, Wang ST, et al. Paclitaxel (Taxol) upregulates expression of functional interleukin-6 in human ovarian cancer cells through multiple signaling pathways. Oncogene. 2006;25:4857–4866
  11. Chao A, Wang TH, Lee YS, Hsueh S, Chao AS, Chang TC, et al. Molecular characterization of adenocarcinoma and squamous carcinoma of the uterine cervix using microarray analysis of gene expression. Int. J. Cancer. 2006;119:91–98
  12. Doleshal M, Magotra AA, Choudhury B, Cannon BD, Labourier E, Szafranska AE. Evaluation and validation of total RNA extraction methods for MicroRNA expression analyses in formalin-fixed, paraffin-embedded tissues. J. Mol. Diagn. 2008;10:203–211
  13. Wang H, Ach RA, Curry B. Direct and sensitive miRNA profiling from low-input total RNA. RNA. 2007;13:151–159
  14. Tetzlaff MT, Liu A, Xu X, Master SR, Baldwin DA, Tobias JW, et al. Differential expression of miRNAs in papillary thyroid carcinoma compared to multinodular goiter using formalin fixed paraffin embedded tissues. Endocr. Pathol. 2007;18:163–173
  15. Hoefig KP, Thorns C, Roehle A, Kaehler C, Wesche KO, Repsilber D, et al. Unlocking pathology archives for microRNA-profiling. Anticancer Res. 2008;28:119–123
  16. Li J, Smyth P, Flavin R, Cahill S, Denning K, Aherne S, et al. Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells. BMC Biotechnol. 2007;7:36
  17. Masuda N, Ohnishi T, Kawamoto S, Monden M, Okubo K. Analysis of chemical modification of RNA from formalin-fixed samples and optimization of molecular biology applications for such samples. Nucleic Acids Res. 1999;27:4436–4443
  18. Gaur A, Jewell DA, Liang Y, Ridzon D, Moore JH, Chen C, et al. Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res. 2007;67:2456–2468
  19. Gillis AJ, Stoop HJ, Hersmus R, Oosterhuis JW, Sun Y, Chen C, et al. High-throughput microRNAome analysis in human germ cell tumours. J. Pathol. 2007;213:319–328
  20. Carlson SG, Eng E, Kim EG, Perlman EJ, Copeland TD, Ballermann BJ, et al. in renal development and Wilms’ tumor. J. Am. Soc. Nephrol. 1998;9:1873–1880
  21. Sontag E, Fedorov S, Kamibayashi C, Robbins D, Cobb M, Mumby M. The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. Cell. 1993;75:887–897
  22. Fukukawa C, Shima H, Tanuma N, Ogawa K, Kikuchi K. Up-regulation of I-2(PP2A)/SET gene expression in rat primary hepatomas and regenerating livers. Cancer Lett. 2000;161:89–95

PII: S0304-3835(09)00627-2

doi: 10.1016/j.canlet.2009.10.005

Cancer Letters
Volume 291, Issue 1 , Pages 99-107 , 1 May 2010

Article Tools

* Image Usage & Resolution