Cancer Letters
Volume 291, Issue 1 , Pages 20-30 , 1 May 2010

Honokiol induces cell apoptosis in human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress

  • Ying-Ju Chen

      Affiliations

    • Institute of Toxicology, National Taiwan University, Taipei, Taiwan, ROC
    • These authors contributed equally to this work.
    • ,
  • Chien-Lin Wu

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Changhua Christian Hospital, Changhua, Taiwan, ROC
    • ,
  • Ju-Fang Liu

      Affiliations

    • Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung, Taiwan, ROC
    • ,
  • Yi-Chin Fong

      Affiliations

    • School of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC
    • Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan, ROC
    • Department of Orthopaedic, China Medical University Hospital, Taichung, Taiwan, ROC
    • These authors contributed equally to this work.
    • ,
  • Sheng-Feng Hsu

      Affiliations

    • Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan, ROC
    • ,
  • Te-Mao Li

      Affiliations

    • Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan, ROC
    • ,
  • Yi-Chang Su

      Affiliations

    • Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan, ROC
    • ,
  • Shing-Hwa Liu

      Affiliations

    • Institute of Toxicology, National Taiwan University, Taipei, Taiwan, ROC
    • Corresponding Author InformationCorresponding authors. Address: Department of Pharmacology, College of Medicine, China Medical University, No. 91, Hsueh-Shih Road, Taichung, Taiwan, ROC. Tel.: +886 4 22053366x2228; fax: +886 4 22053764 (C.-H. Tang).
    • ,
  • Chih-Hsin Tang

      Affiliations

    • Department of Pharmacology, China Medical University, Taichung, Taiwan, ROC
    • Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan, ROC
    • Corresponding Author InformationCorresponding authors. Address: Department of Pharmacology, College of Medicine, China Medical University, No. 91, Hsueh-Shih Road, Taichung, Taiwan, ROC. Tel.: +886 4 22053366x2228; fax: +886 4 22053764 (C.-H. Tang).

Received 16 May 2009 ,Revised 25 August 2009 ,Accepted 25 August 2009.

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PII: S0304-3835(09)00625-9

doi: 10.1016/j.canlet.2009.08.032

Cancer Letters
Volume 291, Issue 1 , Pages 20-30 , 1 May 2010

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