Cancer Letters
Volume 291, Issue 1 , Pages 83-89 , 1 May 2010

Enhanced antitumor effects by combination gene therapy using MDR1 gene shRNA and HSV1-tk in a xenograft mouse model

  • Sang-Woo Lee

      Affiliations

    • Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea
    • These authors contributed equally to this work.
  • ,
  • You La Lee

      Affiliations

    • Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea
    • These authors contributed equally to this work.
  • ,
  • Yong Jin Lee

      Affiliations

    • Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea
  • ,
  • Seung-Yoon Park

      Affiliations

    • Department of Biochemistry, School of Medicine, Dongguk University, Kyungju 780-714, Republic of Korea
  • ,
  • In-San Kim

      Affiliations

    • Department of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea
  • ,
  • Tae Hyun Choi

      Affiliations

    • Radiological and Medical Sciences Research Center, Korea Institute of Radiological and Medical Sciences, Seoul 139-709, Republic of Korea
  • ,
  • Jeoung-Hee Ha

      Affiliations

    • Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea
  • ,
  • Byeong-Cheol Ahn

      Affiliations

    • Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea
  • ,
  • Jaetae Lee

      Affiliations

    • Department of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea
    • Corresponding Author InformationCorresponding author. Tel.: +82 53 420 5586; fax: +82 53 422 0864.

Received 31 August 2009 ,Revised 2 October 2009 ,Accepted 5 October 2009.

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PII: S0304-3835(09)00623-5

doi: 10.1016/j.canlet.2009.10.002

Cancer Letters
Volume 291, Issue 1 , Pages 83-89 , 1 May 2010