Cancer Letters
Volume 291, Issue 1 , Pages 67-75 , 1 May 2010

Selective targeting of HPV-16 E6/E7 in cervical cancer cells with a potent oncolytic adenovirus and its enhanced effect with radiotherapy in vitro and vivo

  • Wei Wang

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
    • These authors contributed equally to this manuscript.
  • ,
  • Ni Sima

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
    • Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, PR China
    • These authors contributed equally to this manuscript.
  • ,
  • Debo Kong

      Affiliations

    • The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, PR China
  • ,
  • Aiyue Luo

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Qinglei Gao

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Shujie Liao

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Wei Li

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Lingfei Han

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Juan Wang

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Shixuan Wang

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Yunping Lu

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Daowen Wang

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Gang Xu

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Jianfeng Zhou

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
  • ,
  • Li Meng

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
    • Corresponding Author InformationCorresponding authors. Fax: +86 (27) 83662681.
  • ,
  • Ding Ma

      Affiliations

    • Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, PR China
    • Corresponding Author InformationCorresponding authors. Fax: +86 (27) 83662681.

Received 7 September 2009 ,Accepted 30 September 2009.

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PII: S0304-3835(09)00621-1

doi: 10.1016/j.canlet.2009.09.022

Cancer Letters
Volume 291, Issue 1 , Pages 67-75 , 1 May 2010