Cancer Letters
Volume 286, Issue 2 , Pages 206-216 , 28 December 2009

MKP1 repression is required for the chemosensitizing effects of NF-κB and PI3K inhibitors to cisplatin in non-small cell lung cancer

  • María Cortes-Sempere

      Affiliations

    • Translational Oncology Unit C.S.I.C./U.A.M: Instituto de Investigaciones Biomédicas C.S.I.C./U.A.M., C/Arturo Duperier, 4, Madrid 28029, Spain
    • CIBER de Enfermedades Raras (CIBERER) Valencia, C/Álvaro de Bazán, 10 Valencia, Spain
    • These authors contributed equally to this manuscript.
    • ,
  • Sharmila Chattopadhyay

      Affiliations

    • Department of Pathology, University of California, San Diego, CA, United States
    • These authors contributed equally to this manuscript.
    • ,
  • Ana Rovira

      Affiliations

    • Medical Oncology Department, Hospital del Mar-IMAS, Barcelona, Spain
    • Cancer Research Program, IMIM-Hospital del Mar, PRBB, Barcelona, Spain
    • ,
  • Vanessa Rodriguez-Fanjul

      Affiliations

    • Translational Oncology Unit C.S.I.C./U.A.M: Instituto de Investigaciones Biomédicas C.S.I.C./U.A.M., C/Arturo Duperier, 4, Madrid 28029, Spain
    • CIBER de Enfermedades Raras (CIBERER) Valencia, C/Álvaro de Bazán, 10 Valencia, Spain
    • ,
  • Cristobal Belda-Iniesta

      Affiliations

    • Medical Oncology Department, Hospital La Paz, Madrid, Spain
    • ,
  • Marian Tapia

      Affiliations

    • Medical Oncology Department, Hospital del Mar-IMAS, Barcelona, Spain
    • Cancer Research Program, IMIM-Hospital del Mar, PRBB, Barcelona, Spain
    • ,
  • Paloma Cejas

      Affiliations

    • Medical Oncology Department, Hospital La Paz, Madrid, Spain
    • ,
  • Rosario Machado-Pinilla

      Affiliations

    • Translational Oncology Unit C.S.I.C./U.A.M: Instituto de Investigaciones Biomédicas C.S.I.C./U.A.M., C/Arturo Duperier, 4, Madrid 28029, Spain
    • CIBER de Enfermedades Raras (CIBERER) Valencia, C/Álvaro de Bazán, 10 Valencia, Spain
    • ,
  • Cristina Manguan-García

      Affiliations

    • Translational Oncology Unit C.S.I.C./U.A.M: Instituto de Investigaciones Biomédicas C.S.I.C./U.A.M., C/Arturo Duperier, 4, Madrid 28029, Spain
    • CIBER de Enfermedades Raras (CIBERER) Valencia, C/Álvaro de Bazán, 10 Valencia, Spain
    • ,
  • Isabel Sánchez-Pérez

      Affiliations

    • Translational Oncology Unit C.S.I.C./U.A.M: Instituto de Investigaciones Biomédicas C.S.I.C./U.A.M., C/Arturo Duperier, 4, Madrid 28029, Spain
    • CIBER de Enfermedades Raras (CIBERER) Valencia, C/Álvaro de Bazán, 10 Valencia, Spain
    • ,
  • Manuel Nistal

      Affiliations

    • Pathology Department Hospital La Paz, Madrid, Spain
    • ,
  • Carmen Moratilla

      Affiliations

    • Translational Oncology Unit C.S.I.C./U.A.M: Instituto de Investigaciones Biomédicas C.S.I.C./U.A.M., C/Arturo Duperier, 4, Madrid 28029, Spain
    • ,
  • Javier de Castro-Carpeño

      Affiliations

    • Medical Oncology Department, Hospital La Paz, Madrid, Spain
    • ,
  • Manuel Gonzalez-Barón

      Affiliations

    • Medical Oncology Department, Hospital La Paz, Madrid, Spain
    • ,
  • Joan Albanell

      Affiliations

    • Medical Oncology Department, Hospital del Mar-IMAS, Barcelona, Spain
    • Cancer Research Program, IMIM-Hospital del Mar, PRBB, Barcelona, Spain
    • ,
  • Rosario Perona

      Affiliations

    • Translational Oncology Unit C.S.I.C./U.A.M: Instituto de Investigaciones Biomédicas C.S.I.C./U.A.M., C/Arturo Duperier, 4, Madrid 28029, Spain
    • CIBER de Enfermedades Raras (CIBERER) Valencia, C/Álvaro de Bazán, 10 Valencia, Spain
    • Corresponding Author InformationCorresponding author. Address: Translational Oncology Unit C.S.I.C./U.A.M: Instituto de Investigaciones Biomédicas C.S.I.C./U.A.M., C/Arturo Duperier, 4, Madrid 28029, Spain. Tel.: +34 91 5854463; fax: +34 91 5854401.

Received 12 January 2009 ,Revised 21 May 2009 ,Accepted 25 May 2009.

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PII: S0304-3835(09)00376-0

doi: 10.1016/j.canlet.2009.05.029

Cancer Letters
Volume 286, Issue 2 , Pages 206-216 , 28 December 2009

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