« Previous
Next »
Cancer Letters
Volume 286, Issue 1
, Pages 38-43
, 1 December 2009
Hepatic iron overload and hepatocellular carcinoma
References
- . Survival and causes of death in hemochromatosis: observations in 163 patients. Ann. N.Y. Acad. Sci. 1988;526:245–257
- . Survival and causes of death in cirrhotic and non-cirrhotic patients with primary hemochromatosis. N. Engl. J. Med. 1985;313:1256–1262
- Cohort study of internal malignancy in genetic hemochromatosis and other chronic non-alcoholic liver diseases. J. Natl. Cancer Inst. 1985;75:81–84
- . Siderosis in the Bantu: a combined histopathological and chemical study. Arch. Path. 1960;70:279–292
- . Siderosis in the Bantu: a comparison of incidence in males and females. Br. Med. J. 1962;1:522–524
- Dietary iron overload in southern African rural blacks. S. Afr. Med. J. 1990;78:301–305
- . Primary carcinoma of the liver in Africa. Br. J. Cancer. 1956;10:609–622
- . Pathogenesis of liver cancer in the Johannesburg area (S. Africa). Acta Unio Internationalis Contra Cancrum. 1957;13:590–598
- . The geographic pathology of primary liver cancer. Cancer Res. 1963;23:1624–1633
- . Associations of iron overload in Africa and hepatocellular carcinoma and tuberculosis. Blood. 1996;87:3470–3476
- African iron overload and hepatocellular carcinoma. Eur. J. Haematol. 1998;60:28–34
- Dietary iron overload as a risk factor for hepatocellular carcinoma in Black Africans. Hepatology. 1998;27:1563–1566
- . Iron-free neoplastic nodules and hepatocellular carcinoma without cirrhosis in Wistar rats fed a diet high in iron. J. Pathol. 2006;208:82–90
- . Hepatocellular carcinoma caused by iron overload: a possible mechanism of direct hepatocarcinogenicity. Toxicology. 2006;219:41–52
- . Cancer risk following primary hemochromatosis: a population-based cohort study in Denmark. Int. J. Cancer. 1995;60:160–162
- . Hepatocellular carcinoma in hereditary hemochromatosis. Can. J. Gastroenterol. 1998;129:946–995
- . Iron, hemochromatosis, and hepatocellular carcinoma. Gastroenterology. 2004;127:S79–S86
- . Long-term survival analysis in hereditary hemochromatosis. Gastroenterology. 1991;101:368–372
- . Long-term results of venesection therapy in idiopathic hemochromatosis. Quart. J. Med. 1967;45:611–623
- . The relationship between hepatocellular carcinoma and cirrhosis. Semin. Liver Dis. 1984;4:136–146
- . Cirrhosis and hepatoma occurring at Boston City Hospital (1917–1968). Cancer. 1973;32:458–462
- . Hepatic fibrosis: a clinico-pathological review of 520 cases. J. Clin. Pathol. 1973;26:9369–9942
- Primary hepatocellular carcinoma in idiopathic hemochromatosis: occurrence in non-cirrhotic patients. Gastroenterology. 1988;95:1399–1402
- . Iron and neoplasia. J. Hepatol. 1998;28:21–25
- . Hepatocellular carcinoma arising in a non-cirrhotic liver in genetic hemochromatosis: three case reports and a review of the literature. Eur. J. Gastroenterol. 1999;11:915–919
- . Hepatocellular carcinoma in a patient with hereditary hemochromatosis and non-cirrhotic liver. A case report. Pathol. Res. Pract. 1999;195:509–513
- . Hepatocellular carcinoma in a patient with hereditary hemochromatosis without cirrhosis. Gastroenterol. Hepatol. 2001;234:132–134
- . Hepatocellular carcinoma arising in a non-cirrhotic liver in genetic hemochromatosis. Scand. J. Gastroenterol. 2000;35:889–893
- Increased cancer risk in a cohort of 230 patients with hereditary hemochromatosis in comparison to matched control patients with non-iron-related chronic liver disease. Hepatology. 2001;33:647–665
- A.S. Strachan, Hemosiderosis and hemochromatosis in South African natives with a comment on the aetiology of hemochromatosis, MD Thesis, University of Glasgow, Glasgow, Scotland, 1929.
- . Iron overload in the South African Bantu. Trans. Roy. Soc. Trop. Med. Hyg. 1953;47:536–548
- . Dietary iron overload persists in rural sub-Saharan Africa. Lancet. 1986;1:1310–1313
- Traditional beer consumption and the iron status of spouse pairs from a rural community in Zimbabwe. Blood. 1997;89:2159–2166
- . Changing patterns of dietary iron overload in Black South Africans. Am. J. Clin. Nutr. 1979;32:1272–1278
- . Iron overload in Bantu subjects. Studies on the availability of iron in Bantu beer. Am. J. Clin. Nutr. 1964;14:47–51
- . Measurements of iron status and survival in African iron overload. S. Afr. Med. J. 1999;89:966–972
- . Siderosis in the Bantu: a comparison of incidence in males and females. Br. Med. J. 1962;1:522–524
- . Hepatic iron stores and markers of iron overload in alcoholics and patients with idiopathic hemochromatosis. Dig. Dis. Sci. 1982;27:909–916
- . Distribution of storage iron as body stores expand in patients with hemochromatosis. J. Lab. Clin. Med. 1975;86:479–489
- . Patterns of iron storage in dietary iron overload and idiopathic hemochromatosis. J. Lab. Clin. Med. 1976;88:725–731
- . Siderosis in the Bantu: the relationship between iron overload and cirrhosis. J. Lab. Clin. Med. 1961;58:845–853
- Iron overload in Africa: interaction between a gene and dietary iron content. N. Engl. J. Med. 1992;326:95–100
- . Haemosiderosis in lemurs. Zoo. Biol. 1984;3:255–265
- . Hepatopathy associated with excessive iron storage in Mynah birds. J. Am. Vet. Med. Assoc. 1981;179:1214–1217
- . Beta 2 knockout mice develop parenchymal iron overload: a putative role for class 1 genes of the major histocompatibility complex in iron metabolism. Proc. Natl. Acad. Sci. USA. 1996;93:1529–1534
- . Hereditary spherocytosis with secondary hemochromatosis. Lancet. 1968;2:481–485
- Hepatocellular carcinoma associated with secondary hemochromatosis in a non-cirrhotic liver: a case report. Hepatol. Res. 2003;26:254–258
- Hepatocellular carcinoma in the thalassaemia syndromes. Br. J. Haematol. 2004;124:114–117
- Increased incidence of HFE C282Y mutations in patients with iron overload and hepatocellular carcinoma developed in non-cirrhotic liver. J. Hepatol. 2000;32:805–8112000
- Hepatocellular carcinoma occurring in non-fibrotic liver: epidemiologic and histopathologic analysis of 80 French cases. Hepatology. 2000;32:200–204
- . Pathology of dietary carbonyl iron overload in rats. Lab. Invest. 1987;57:555–563
- . Ultrastructural observation in the carbonyl iron fed rat: an animal model for hemochromatosis. Virchows Arch. B. 1987;53:208–217
- Biochemical and biophysical investigations of the ferrocen iron-loaded rat. An animal model of primary hemochromatosis. Eur. J. Biochem. 1991;202:405–410
- . Iron overload of the liver by trimethyl hexanoyl ferrocene in rats. Acta Anat. 1992;43:96–108
- . Metabolism of iron from (3, 3, 5-trimethyl hexanoyl) ferrocene in rats. Biochem. Pharmacol. 1993;45:385–391
- Preneoplastic significance of hepatic iron-free foci in genetic hemochromatosis: a study of 85 patients. Hepatology. 1993;18:1363–1369
- . Placental glutathione S transferase as a new marker for hepatocarcinogenesis: in vivo short-term screening for hepatocarcinogenesis. Toxicol. Pathol. 1986;15:60–68
- . Preneoplastic lesions in human hepatocarcinogenesis. Liver Int. 2005;25:16–27
- . Iron homeostasis, oxidative stress, and DNA damage. Free Radic. Biol. Med. 1997;23:783–792
- Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma. Hepatology. 2004;39:1663–1672
- . Mutagenesis by the autoxidation of iron with isolated DNA. Proc. Natl. Acad. Sci. USA. 1988;85:3918–3932
- . Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free. Radic. Biol. Med. 1991;11(1):81–128
- . Cytotoxicity and genotoxicity of lipid-oxidation products. Am. J. Clin. Nutr. 1993;57(Suppl.):779–860
- . Lipid peroxidation in cancer. In: Halliwell B, Arouma AI editor. DNA and Free Radicals. London: Ellis Horwood; 1993;p. 109–144
- . Biochemistry of oxygen toxicity. Ann. Rev. Biochem. 1989;58:79–110
- . Reactive oxygen stress, stress-activated kinases and stress signalling in cancer. EMBO Rep. 2002;3:420–425
- Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma. Proc. Natl. Acad. Sci. USA. 1994;91:12808–12812
- . Detection of 1, N2-propanodeoxyguanosine adducts of trans-4-hydroxy-2-nonenal after gavage of trans-4-hydroxy-2-nonenal or induction of lipid peroxidation with carbon tetrachloride in F344 rats. Chem. Biol. Interact. 2001;137(3):269–283
- The effect of iron overload on rat plasma and liver oxidant status. In vivo Biochem. J. 1994;300:799–803
- 8-Hydroxyl guanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions. J. Biol. Chem. 1992;267:166–172
- Expression of 8-hydroxy-2′-deoxyguanosine in chronic liver disease and hepatocellular carcinoma. Liver Int. 2003;23:1781–1789
- . Formation of 8-hydroxy-2′-deoxyguanosine in the DNA of cultured keratinocytes by clinically used doses of narrowband and broadband B and psoralen plus ultraviolet light. Cancer Sci. 2006;97:99–105
- . Misreading of DNA templates containing 8-hydroxydeoxguanosine at the modifies base and at adjacent residues. Nature. 1989;327(6117):77–79
- . P53 mutations in British patients withy hepatocellular carcinoma: clustering in genetic hemochromatosis. Gastroenterology. 1999;117:154–160
- Oxidative stress and p53 mutations in the carcinogenesis of iron-overload-associated hepatocellular carcinoma. J. Natl. Cancer Inst. 2001;93:1652–1655
- Increased p53 mutation load in non-tumorous human liver of Wilson disease and haemochromatosis: oxyradical overload disease. Proc. Natl. Acad. Sci. USA. 2000;97:12770–12775
- . Inducible nitric oxide synthase could be responsible for resistance or sensitivity to IFN-gamma-induced apoptosis in several human hepatoma cell lines. J. Interferon Cytokine Res. 2006;26:901–913
- . Nitric oxide in liver diseases: friend, foe, or just passer-by?. Ann. N.Y. Acad. Sci. 2002;962:275–295
- . Cellular non-heme iron content is a determinant of nitric oxide-mediated apoptosis, necrosis, and caspase inhibition. J. Biol. Chem. 2000;275:10954–10961
- Iron overload promotes cyclin D1 expression and alters cell cycle in mouse hepatocytes. J. Hepatol. 2006;44:391–399
- . Iron inhibits the non-specific tumoricidal activity of macrophages. A possible contributory mechanism for neoplasia in hemochromatosis. Ann. N.Y. Acad. Sci. 1988;526:301–309
- . Suppressive effect of ferritin on in vitro lymphocyte function. Br. J. Hematol. 1979;42:443–448
- . Synergistic interaction between aflatoxin B1 and hepatitis B virus in hepatocarcinogenesis. Liver Int. 2003;23:1–5
- . Interaction between aflatoxin B1 and dietary iron overload in hepatic mutagenesis. Toxicology. 2007;234:157–166
PII: S0304-3835(08)00874-4
doi: 10.1016/j.canlet.2008.11.001
© 2008 Elsevier Ireland Ltd. All rights reserved.
« Previous
Next »
Cancer Letters
Volume 286, Issue 1
, Pages 38-43
, 1 December 2009
