Cancer Letters
Volume 262, Issue 1 , Pages 114-122 , 8 April 2008

Induction of apoptosis accompanying with G1 phase arrest and microtubule disassembly in human hepatoma cells by jaspolide B, a new isomalabaricane-type triterpene

Received 25 July 2007 ,Revised 31 October 2007 ,Accepted 26 November 2007.

References 

  1. Cragg GM, Newman DJ, Weiss RB. Coral reefs, forests, and thermal vents: the worldwide exploration of nature for novel antitumor agents. Semin. Oncol. 1997;24:156–163
  2. Grabley S, Thiericke R. Bioactive agents and natural sources: trends in discovery and application. Adv. Biochem. Eng. Biotechnol. 1999;64:101–154
  3. Uriz MJ, Turon X, Becerro MA, Galera J. Feeding deterrence in sponges. The role of toxicity, physical defenses, energetic contents, and life-history stage. J. Exp. Mar. Biol. Ecol. 1996;205:187–204
  4. Davis AR, Butler AJ, van Altena I. Settlement behaviour of ascidian larvae: preliminary evidence for inhibition by sponge allelochemicals. Mar. Ecol. Prog. Ser. 1991;72:117–123
  5. Becerro MA, Turon X, Uriz MJ. Multiple functions for secondary metabolites in encrusting marine invertebrates. J. Chem. Ecol. 1997;23:1527–1547
  6. Zhang W, Zhang X, Cao X, Xu J, Zhao Q, Yu X, et al. Optimizing the formation of in vitro sponge primmorphs from the Chinese sponge Stylotella agminata (Ridley). J. Biotechnol. 2003;100:161–168
  7. Freitas JC, Rodrigue F, Lavaud P, Mencia-Huerta JM, Braquet P. Inhibition of platelet aggregation by manoalide: preliminary results. Braz. J. Med. Biol. Res. 1988;21:337–340
  8. Takai A. Okadaic acid, Protein phosphatase inhibition and muscle contractile effects. J. Muscle Res. Cell Motil. 1988;9:563–565
  9. Liu WK, Ho JCK, Che CT. Apoptotic activity of isomalabaricane triterpenes on human promyelocytic leukemia HL60 cells. Cancer Lett. 2005;203:102–110
  10. Bourguet-Kondracki ML, Longeon A, Debitus C, Guyot M. New cytotoxic isomalabaricane-type sesterterpenes from the new caledonian marine sponge Rhabdastrella globostellata. Tetrahedron Lett. 2000;41:3087–3090
  11. Meragelman KM, McKee TC, Boyd MR. New cytotoxic isomalabaricane triterpenes from the sponge Jaspis species. J. Nat. Prod. 2001;64:389–392
  12. McKee TC, Bokesch HR, McCormick JL, Rashid MA, Spielvogel D, Gustafson KR, et al. Isolation and characterization of new anti-HIV and cytotoxic leads from plants, marine, and microbial organisms. J. Nat. Prod. 1997;60:431–438
  13. Tasdemir D, Mangalindan GC, Concepcion GP, Verbitski SM, Rabindran S, Miranda M, et al. Bioactive isomalabaricane triterpenes from the marine sponge Rhabdastrella globostellata. J. Nat. Prod. 2002;65:210–214
  14. Tang SA, Pei Y, Fu HZ, Deng ZW, Li J, Proksch P, et al. Jaspolides A–F, six new isomalabricane-type terpenoids from the sponge Jaspis sp.. Chem. Pharm. Bull. 2006;54:4–8
  15. Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, et al. New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. 1990;82:1107–1112
  16. Ghosh RN, Grove L, Lapets O. A quantitative cell-based high-content screening assay for the epidermal growth factor receptor-specific activation of mitogen-activated protein kinase. Assay Drug Dev. Technol. 2004;2:473–481
  17. Li M, Cui JR, Ye Y, Min JM, Zhang LH, Wang K, et al. Antitumor activity of Z-ajoene, a natural compound purified from garlic: antimitotic and microtubule-interaction properties. Carcinogenesis. 2002;23:573–579
  18. Green DR, Reed JC. Mitochondria and apoptosis. Science. 1998;281:1309–1312
  19. Kroemer G, Dallaporta B, Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol. 1998;60:619–642
  20. Camilleri-Broet S, Vanderwerff H, Caldwell E, Hockenbery D. Distinct alterations in mitochondrial mass and function characterize different models of apoptosis. Exp. Cell Res. 1998;239:277–292
  21. Gourlay CW, Ayscough KR. A role for actin in aging and apoptosis. Biochem. Soc. Trans. 2005;33:1260–1264
  22. Hayashi S, Takeuchi K, Suzuki S, Tsunoda T, Tanaka C, Majima Y. Effect of thrombin on permeability of human epithelial cell monolayers. Pharmacology. 2006;76:46–52
  23. Earnshaw WC. Nuclear changes in apoptosis. Curr. Opin. Cell Biol. 1995;7:337–343
  24. Carnero A. Targeting the cell cycle for cancer therapy. Br. J. Cancer. 2002;87:129–133
  25. Geldof AA, Mastbergen SC, Henrar RE, Faircloth GT. Cytotoxicity and neurocytotoxicity of new marine anticancer agents evaluated using in vitro assays. Cancer Chemother. Pharmacol. 1999;44:312–318
  26. Xu MJ, Cui JR, Fu HZ, Peter P, Lin WH, Li M. Embelin derivatives and their anticancer activity through microtubule disassembly. Planta Med. 2005;71:944–948
  27. Farias SE, Armelin HA. Glucocorticoid hormone renders a rat glioma cell line sensitive to a G1 phase block by microtubule disrupting agents. Braz. J. Med. Biol. Res. 1982;15:231–238
  28. Lee JH, Kang GH, Kim KC, Kim KM, Park DI, Choi BT, et al. Tetrandrine-induced cell cycle arrest and apoptosis in A549 human lung carcinoma cells. Int. J. Oncol. 2002;21:1239–1244
  29. Tanaka H, Takenaka H, Yamao F, Yagura T. Aphidicolin induces alterations in Golgi complex and disorganization of microtubules of HeLa cells upon long-term administration. J. Cell. Physiol. 1998;176:602–611
  30. Russu WA. Thiazolidinedione anti-cancer activity: Is inhibition of microtubule assembly implicated?. Med. Hypotheses. 2007;68:343–346
  31. Casini A, Scozzafava A, Mastrolorenzo A, Supuran LT. Sulfonamides and sulfonylated derivatives as anticancer agents. Curr. Cancer Drug Targets. 2002;2:55–75
  32. Sablina AA, Agapova LS, Chumakov PM, Kopnin BP. p53 does not control the spindle assembly cell cycle checkpoint but mediates G1 arrest in response to disruption of microtubule system. Cell Biol. Int. 1999;23:323–334
  33. Wang HZ, Liu YD, Gao XL, Carter CL, Liu ZR. The recombinant β subunit of C-phycocyanin inhibits cell proliferation and induces apoptosis. Cancer Lett. 2007;247:150–158
  34. Bai RL, Paull KD, Herald CL, Malspeis L, Pettit GR, Hamel E. Halichondrin B and homohalichondrin B, marine natural products binding to the Vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data. J. Biol. Chem. 1991;266:15882–15889
  35. Garcia-Rocha M, Garcia-Gravalos MD, Avila J. Characterisation of antimitotic products from marine organisms that disorganise the microtubule network: ecteinascidin. 743, isohomohalichondrin-B and LL-15. Br. J. Cancer. 1996;73:875–883
  36. Islam MN, Iskander MN. Microtubulin binding sites as target for developing anticancer agents. Mini Rev. Med. Chem. 2004;4:1077–1104

PII: S0304-3835(07)00585-X

doi: 10.1016/j.canlet.2007.11.039

Cancer Letters
Volume 262, Issue 1 , Pages 114-122 , 8 April 2008