Cancer Letters
Volume 253, Issue 1 , Pages 115-123 , 8 August 2007

Exploitation of drug-induced Bcl-2 overexpression for restoring normal apoptosis function: A promising new approach to the treatment of multidrug resistant cancer

  • Yaming Su

      Affiliations

    • Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    • ,
  • Xiaoping Zhang

      Affiliations

    • Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    • ,
  • Patrick J. Sinko

      Affiliations

    • Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA
    • The Cancer Institute of New Jersey, New Brunswick, NJ, USA
    • Corresponding Author InformationCorresponding author. Address: Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA. Tel.: +1 732 445 3831x213; fax: +1 732 445 4271.

Received 28 September 2006 ,Revised 16 January 2007 ,Accepted 18 January 2007.

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☆ This work was support by The Parke-Davis Endowed Chair in Pharmaceutics and Drug Delivery and NIH AI51214.

PII: S0304-3835(07)00031-6

doi: 10.1016/j.canlet.2007.01.018

Cancer Letters
Volume 253, Issue 1 , Pages 115-123 , 8 August 2007

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