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Cancer Letters
Volume 243, Issue 2
, Pages 193-201
, 18 November 2006
mtDNA mutations in invasive cervix tumors: A retrospective analysis
References
- . The epidemiology of cervical cancer. Cancer J. 2003;9:348–359
- The importance of hemoglobin levels during radiotherapy for carcinoma of the cervix. Cancer. 1999;86:1528–1536
- Effect of tumor size on the prognosis of carcinoma of the uterine cervix treated with irradiation alone. Cancer. 1992;69:2796–2806
- Identification of prognostic factors and risk groups in patients found to have nodal metastasis at the time of radical hysterectomy for early-stage squamous carcinoma of the cervix. Gynecol. Oncol. 1989;35:130–135
- Tumor angiogenesis in stage IB cervical cancer: correlation of microvessel density with survival. Am. J. Obstet. Gynecol. 1998;178:314–319
- . Vascular endothelial growth factor (VEGF) expression is a prognostic factor for radiotherapy outcome in advanced carcinoma of the cervix. Br. J. Cancer. 2000;83:620–625
- . Intratumoral pO2-measurements as predictive assay in the treatment of carcinoma of the uterine cervix. Radiother. Oncol. 1999;53:99–104
- Oxygenation predicts radiation response and survival in patients with cervix cancer. Radiother. Oncol. 1998;48:149–156
- . Hypoxia and radiation response in human tumors. Semin. Radiat. Oncol. 1996;6:3–9
- . Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis. Br. J. Cancer. 2000;83:354–359
- . Mutant p53 in patients with invasive cervical cancer stages IB to IIB. Gynecol. Oncol. 1995;57:212–214
- Prognostic significance of immunohistochemically detected p53 protein expression in stage IIIB squamous cell carcinoma of the uterine cervix treated with radiation therapy alone. Gynecol. Oncol. 1996;63:216–218
- . Aberrant expression of the cell cycle associated proteins TP53, MDM2, p21, p27, cdk4, cyclin D1, RB, and EGFR in cervical carcinomas. Gynecol. Oncol. 1999;73:223–228
- Expression of cyclins, p53, and Ki-67 in cervical squamous cell carcinomas: overexpression of cyclin A is a poor prognostic factor in stage Ib and II disease. Virchows Arch. 2005;446:626–633
- . Role of the retinoblastoma family in gynecological cancer. Cancer Biol. Ther. 2003;2:636–641
- . Relation between HPV-DNA and expression of p53, bcl-2, p21WAF-1, MIB-1, HER-2/neu and DNA ploidy in early cervical carcinoma: correlation with clinical outcome. Oncol. Rep. 2004;12:169–176
- . Association of p27Kip1, cyclin E and c-myc expression with progression and prognosis in HPV-positive cervical neoplasms. Anticancer Res. 1998;18:3991–3998
- High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples. Int. J. Cancer. 2001;93:534–538
- Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science. 2000;287:2017–2019
- Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat. Genet. 1998;20:291–293
- Mutations of the D310 mitochondrial mononucleotide repeat in primary tumors and cytological specimens. Cancer Lett. 2003;190:73–77
- . Mitochondrial diseases in man and mouse. Science. 1999;283:1482–1488
- . The oxidative phosphorylation (OXPHOS) system: nuclear genes and human genetic diseases. Bioessays. 2001;23:518–525
- . Mitochondrial genetics and disease. Trends Biochem. Sci. 2000;25:555–560
- . Mitochondrial genetic control of assembly and function of complex I in mammalian cells. J. Bioenerg. Biomembr. 2001;33:251–257
- Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates. Cancer Res. 2001;61:7623–7626
- Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors. Cancer Res. 2001;61:7015–7019
- Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours. Oncogene. 2000;19:2060–2066
- . High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection. Nat. Genet. 2001;28:147–150
- . Inherent radiosensitivity testing of tumor biopsies obtained from patients with carcinoma of the cervix or endometrium. Radiother. Oncol. 1991;22:201–205
- . MITOMAP: a human mitochondrial genome database—2004 update. Nucleic Acids Res. 2005;33(Database Issue):D611–D613
- . The determination of complete human mitochondrial DNA sequences in single cells: implications for the study of somatic mitochondrial DNA point mutations. Nucleic Acids Res. 2001;29:E74
- . Mitochondrial DNA complex I and III mutations associated with Leber's hereditary optic neuropathy. Genetics. 1992;130:163–173
- . Phylogenetic analysis of the mitochondrial genomes from Leber hereditary optic neuropathy pedigrees. Genetics. 1995;140:285–302
- Novel mutations of mitochondrial complex I in pathologically proven Parkinson disease. Neurogenetics. 1998;1:197–204
- . Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer. Cancer Res. 2002;62:972–976
- . Mitochondrial DNA mutation correlates with stage progression and prognosis in non-small cell lung cancer. Hum. Mutat. 2003;21:441–443
- . Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications. Leukemia. 2003;17:1437–1447
- . Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid. Carcinogenesis. 2005;26:145–152
- High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas. Cancer Res. 2001;61:5998–6001
- . Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis. Carcinogenesis. 2003;24:1481–1487
- . Regulatory polymorphisms underlying complex disease traits. J. Mol. Med. 2005;83:97–109
- . Mitochondrial genetic control of assembly and function of complex I in mammalian cells. J. Bioenerg. Biomembr. 2001;33:251–257
- Genetic and functional analysis of mitochondrial DNA-encoded complex I genes. Ann. NY Acad. Sci. 2004;1011:272–283
- . Mitochondrial genetics and human disease. Bioessays. 1996;18:983–991
- . Mitochondrial dysfunction is a common phenotype in aging and cancer. Ann. NY Acad. Sci. 2004;1019:260–264
- . Understanding aging: revealing order out of chaos. Biochim. Biophys. Acta. 2004;1658:122–132
- Definitive evidence for hypoxic cells influencing cure in cancer therapy. Br. J. Cancer Suppl. 1978;37:302–306
- The importance of hemoglobin levels during radiotherapy for carcinoma of the cervix. Cancer. 1999;86:1528–1536
- . Flow cytometric analysis of DNA ploidy and S-phase fraction of Stage IIIB cervical carcinoma. Eur. J. Gynaecol. Oncol. 2004;25:428–430
- . Tumour cell kinetics as a prognostic factor in squamous cell carcinoma of the cervix treated with radiotherapy. Radiother. Oncol. 1999;50:77–84
- . No prognostic impact of flow-cytometric measured DNA ploidy and S-phase fraction in cancer of the uterine cervix: a prospective study of 465 patients. Gynecol. Oncol. 1995;57:79–85
- . In silico p53 mutation hotspots in lung cancer. Carcinogenesis. 2004;25:1099–1107
PII: S0304-3835(05)01044-X
doi: 10.1016/j.canlet.2005.11.035
© 2005 Elsevier Ireland Ltd. All rights reserved.
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Cancer Letters
Volume 243, Issue 2
, Pages 193-201
, 18 November 2006
