Cancer Letters
Volume 241, Issue 1 , Pages 87-92 , 8 September 2006

Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts

  • Akemi Gunji

      Affiliations

    • Biochemistry Division, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
    • Department of Oral Surgery, Tokyo Medical and Dental University Graduate School, Bunkyo-ku, Tokyo, Japan
    • ,
  • Akiko Uemura

      Affiliations

    • Biochemistry Division, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
    • ADP-ribosylation in Oncology Project, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
    • ,
  • Masahiro Tsutsumi

      Affiliations

    • Department of Oncological Pathology, Cancer Center, Nara Medical University, 840, Shijo-cho, Kashihara, Nara 634-8521, Japan
    • ,
  • Tadashige Nozaki

      Affiliations

    • Biochemistry Division, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
    • ,
  • Osamu Kusuoka

      Affiliations

    • Department of Oncological Pathology, Cancer Center, Nara Medical University, 840, Shijo-cho, Kashihara, Nara 634-8521, Japan
    • ,
  • Ken Omura

      Affiliations

    • Department of Oral Surgery, Tokyo Medical and Dental University Graduate School, Bunkyo-ku, Tokyo, Japan
    • Department of Advanced Molecular Diagnosis and Maxillofacial Surgery, Hard Tissue Genome Research Center, Tokyo Medical and Dental University
    • ,
  • Hiroshi Suzuki

      Affiliations

    • Chugai Pharmaceutical Co. Ltd. Gotemba, 1-135, Komakado, Gotemba, Shizuoka, 412-0038, Japan
    • ,
  • Hitoshi Nakagama

      Affiliations

    • Biochemistry Division, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
    • ,
  • Takashi Sugimura

      Affiliations

    • Biochemistry Division, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
    • ,
  • Mitsuko Masutani

      Affiliations

    • Biochemistry Division, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
    • ADP-ribosylation in Oncology Project, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
    • Corresponding Author InformationCorresponding author. Address: ADP-ribosylation in Oncology Project, National Cancer Center Research Institute, 1-1, Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan. Tel.: +81 3 3542 2511x4551; fax: +81 3 3542 2530.

Received 28 July 2005 ,Revised 2 October 2005 ,Accepted 7 October 2005.

References 

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PII: S0304-3835(05)00910-9

doi: 10.1016/j.canlet.2005.10.003

Cancer Letters
Volume 241, Issue 1 , Pages 87-92 , 8 September 2006

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