Cancer Letters
Volume 228, Issue 1 , Pages 65-69 , 18 October 2005

Oligogenic inheritance in neuroblastoma

  • Luca Longo

      Affiliations

    • Paediatric Translational Oncology, National Institute for Cancer Research (IST), Genoa, Italy
    • ,
  • Gian Paolo Tonini

      Affiliations

    • Paediatric Translational Oncology, National Institute for Cancer Research (IST), Genoa, Italy
    • ,
  • Isabella Ceccherini

      Affiliations

    • Laboratory of Molecular Genetics, G. Gaslini Institute, Genoa, Italy
    • ,
  • Patrizia Perri

      Affiliations

    • Laboratory of Neuroblastoma Research, Fondazione Italiana per la Lotta al Neuroblastoma c/o Advanced Biotechnology Center (CBA), Genoa, L.go R. Benzi, 10, 16132, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +39 010 57 37 430; fax: +39 010 57 37 463.

Received 22 November 2004 ,Accepted 2 December 2004.

References 

  1. D'Angio GJ, Evans AE, Koop CE. Special pattern of widespread neuroblastoma with a favourable prognosis. Lancet. 1971;1:1046–1049
  2. Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B. Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee. Cancer. 1999;86:349–363
  3. Clausen N, Andersson P, Tommerup N. Familial occurrence of neuroblastoma, von Recklinghausen's neurofibromatosis, Hirschsprung's agangliosis and jaw-winking syndrome. Acta Paediatr. Scand. 1989;78:736–741
  4. Rohrer T, Trachsel D, Engelcke G, Hammer J. Congenital central hypoventilation syndrome associated with Hirschsprung's disease and neuroblastoma: case of multiple neurocristopathies. Pediatr. Pulmonol. 2002;33:71–76
  5. Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM. Amplification of N-MYC in untreated human neuroblastomas correlates with advanced disease stage. Science. 1984;224:1121–1124
  6. White PS, Maris JM, Beltinger C, Sulman E, Marshall HN, Fujimori M, et al. A region of consistent deletion in neuroblastoma within human chromosome 1 p36.2–36.3. Proc. Natl Acad. Sci. USA. 1995;92:5520–5524
  7. Bown N, Cotterill S, Lastowska M, O'Neill S, Pearson AD, Plantaz D, et al. Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma. N. Engl. J. Med. 1999;340:1954–1961
  8. Brodeur GM. Neuroblastoma: biological insights into a clinical enigma. Nat. Rev. Cancer. 2003;3:203–216
  9. Knudson AG, Strong LC. Mutation and cancer: neuroblastoma and pheochromocytoma. Am. J. Hum. Genet. 1972;24:514–532
  10. Trochet D, Bourdeaut F, Janoueix-Lerosey I, Deville A, De Pontual L, Schleiermacher G, et al. Germline mutations of the Paired-Like Homeobox 2B (PHOX2B) gene in neuroblastoma. Am. J. Hum. Genet. 2004;74:761–764
  11. Mosse YP, Laudenslager M, Khazi D, Carlisle AJ, Winter CL, Rappaport E, et al. Germline PHOX2B mutation in hereditary neuroblastoma. Am. J. Hum. Genet. 2004;75:727–730
  12. Maris JM, Kyemba SM, Rebbeck TR, White PS, Sulman EP, Jensen SJ, et al. Familial predisposition to neuroblastoma does not map to chromosome band 1p36. Cancer Res. 1996;56:3421–3425
  13. Tonini GP, McConville C, Cusano R, Rees SA, Dagnino M, Longo L, et al. Exclusion of candidate genes and chromosomal regions in familial neuroblastoma. Int. J. Mol. Med. 2001;7:85–89
  14. Maris JM, Weiss MJ, Mosse Y, Hii G, Guo C, White PS, et al. Evidence for a hereditary neuroblastoma predisposition locus at chromosome 16p12–13. Cancer Res. 2002;62:6651–6658
  15. Perri P, Longo L, McConville C, Cusano R, Rees SA, Seri M, et al. Linkage analysis in families with recurrent neuroblastoma. Ann. NY Acad. Sci. 2002;963:74–84
  16. Perri P, Longo L, Cusano R, McConville CM, Rees SA, Devoto M, et al. Weak linkage at 4p16 to predisposition for human neuroblastoma. Oncogene. 2002;21:8356–8360
  17. Pattyn A, Morin X, Cremer H, Goridis C, Brunet JF. The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature. 1999;399:366–370
  18. V. van Limpt, A. Schramm, A. van Lakeman, P. Sluis, A. Chan, M. van Noesel, F. Baas, H. Caron, A. Egger, R. Versteeg, The Phox2B homeobox gene is mutated in sporadic neuroblastomas, Oncogene 23 (57) (2004) 9280–9288.
  19. P. Perri, T. Bachetti, L. Longo, I. Matera, M. Seri, G.P. Tonini, I. Ceccherini, PHOX2B mutations and genetic predisposition to neuroblastoma, Oncogene 24 (18) (2005) 3050–3053.
  20. Tonini GP, Longo L, Coco S, Perri P. Familial neuroblastoma: a complex heritable disease. Cancer Lett. 2003;197:41–45
  21. Bolk S, Pelet A, Hofstra RM, Angrist M, Salomon R, Croaker D, et al. A human model for multigenic inheritance: phenotypic expression in Hirschsprung disease requires both the RET gene and a new 9q31 locus. Proc. Natl Acad. Sci. USA. 2000;97:268–273
  22. Bolk Gabriel S, Salomon R, Pelet A, Angrist M, Amiel J, Fornage M, et al. Segregation at three loci explains familial and population risk in Hirschsprung disease. Nat. Genet. 2002;31:89–93
  23. Katsanis N. The oligogenic properties of Bardet-Biedl syndrome. Hum. Mol. Genet. 2004;13 Spec. No. 1:R65–R71
  24. Slavotinek A, Biesecker LG. Genetic modifiers in human development and malformation syndromes, including chaperone proteins, Hum. Mol. Genet. 2003;12 Spec. No. 1:45–50
  25. Ming JE, Muenke M. Multiple hits during early embryonic development: digenic diseases and holoprosencephaly. Am. J. Hum. Genet. 2002;71:1017–1032
  26. Robertson CM, Tyrrell JC, Pritchard J. Familial neural crest tumours. Eur. J. Pediatr. 1991;150:789–792

PII: S0304-3835(05)00340-X

doi: 10.1016/j.canlet.2004.12.052

Cancer Letters
Volume 228, Issue 1 , Pages 65-69 , 18 October 2005

Article Tools

* Image Usage & Resolution