Cancer Letters
Volume 234, Issue 2 , Pages 220-231, 28 March 2006

Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases

  • Volker M. Arlt

      Affiliations

    • Section of Molecular Carcinogenesis, Institute of Cancer Research, Brookes Lawley Building, Sutton, Surrey SM2 5NG, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 208 722 4405; fax: +44 208 722 4052.
    • ,
  • Colin J. Henderson

      Affiliations

    • Cancer Research UK Molecular Pharmacology Unit, Biomedical Research Centre, Dundee DD1 9SY, UK
    • ,
  • C. Roland Wolf

      Affiliations

    • Cancer Research UK Molecular Pharmacology Unit, Biomedical Research Centre, Dundee DD1 9SY, UK
    • ,
  • Heinz H. Schmeiser

      Affiliations

    • Division of Molecular Toxicology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    • ,
  • David H. Phillips

      Affiliations

    • Section of Molecular Carcinogenesis, Institute of Cancer Research, Brookes Lawley Building, Sutton, Surrey SM2 5NG, UK
    • ,
  • Marie Stiborova

      Affiliations

    • Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40 Prague 2, The Czech Republic

Received 2 February 2005; received in revised form 20 March 2005; accepted 24 March 2005.

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PII: S0304-3835(05)00278-8

doi:10.1016/j.canlet.2005.03.035

Cancer Letters
Volume 234, Issue 2 , Pages 220-231, 28 March 2006

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