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Cancer Letters
Volume 226, Issue 1
, Pages 37-47
, 8 August 2005
Antitumor effect of gefitinib (‘Iressa’) on esophageal squamous cell carcinoma cell lines in vitro and in vivo
References
- . Estimating the world cancer burden: Globocan 2000. Int. J. Cancer. 2001;94:153–156
- . Oesophageal cancer composed of mixed histological types. Eur. J. Surg. Oncol. 1996;22:225–231
- . Treatment of esophageal carcinoma. Chest. 1999;116(Suppl. 6):463S–465S
- . Multiple management modalities in esophageal cancer: combined modality management approaches. Oncologist. 2004;9:147–159
- . Epidermal growth factor-receptor-protein kinase interactions, co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity. J. Biol. Chem. 1980;255:4834–4842
- . The ErbB receptor tyrosine family as signal integrators. Endocr. Relat. Cancer. 2001;8:151–159
- . Cell signaling by receptor tyrosine kinases. Cell. 2000;103:211–215
- . Untangling the ErbB signaling network. Nat. Rev. Mol. Cell. Biol. 2001;2:127–137
- . Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin. Cancer Res. 2000;6:4885–4892
- ZD1839 (Iressa), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug resistant MCF-7ADR human breast cancer cells. Int. J. Cancer. 2002;98:463–469
- Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa). Clin. Cancer Res. 2002;8:3250–3258
- . Inhibition of epidermal growth factor receptor signaling in malignant pleural methothelioma. Cancer Res. 2002;62:5242–5247
- Prognostic significance of transforming growth factor-alpha in human esophageal carcinoma. Implication for the autocrine proliferation. Cancer. 1993;71:2902–2909
- . High incidence of EGF receptor hyperproduction in esophageal squamous-cell carcinomas. Int. J. Cancer. 1987;39:333–337
- . Prognostic significance of epidermal growth factor receptor in esophageal squamous cell carcinomas. Cancer. 1989;63:2169–2173
- Prognostic factor of oesophageal squamous cell carcinoma from the perspective of molecular biology. Br. J. Cancer. 1999;80:1281–1288
- . Further evidence for prognostic significance of epidermal growth factor receptor gene amplification in patients with esophageal squamous cell carcinoma. Clin. Cancer Res. 1996;2:909–914
- . Prognostic significance of epidermal growth factor receptor in esophageal squamous cell carcinomas. Cancer. 1989;63:2169–2173
- Epidermal growth factor receptor overexpression in esophageal carcinoma. An immunohistochemical study correlated with clinicopathologic findings and DNA amplification. Cancer. 1994;74:795–804
- . Expression of epidermal growth factor receptor and proliferating cell nuclear antigen predicts response of esophageal squamous cell carcinoma to chemotherapy. Cancer. 1994;74:1693–1698
- United States Food and Drug Administration Drug Approval summary: gefitinib (ZD1839; Iressa) tablets. Clin. Cancer Res. 2004;10:1212–1218
- Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (’Iressa’, ZD1839) in Japanese patients with solid malignant tumors. Ann. Oncol. 2003;14:922–930
- Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J. Clin. Oncol. 2003;21:2237–2246
- Angiogenesis as a prognostic marker in breast carcinoma with conventional adjuvant chemotherapy: a multiparametric and immunohistochemical analysis. J. Pathol. 1998;184:130–135
- Sensitivity to gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/Akt pathway for proliferation. Mol. Cancer Ther. 2004;3:465–472
- Gefitinib (’Iressa’, ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, up-regulates p27KIP1 and induces G1 arrest in oral squamous cell carcinoma cell lines. Oral Oncol. 2004;40:43–51
- Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 (’Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells. J. Cell. Physiol. 2003;195:139–150
- . Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas. Cancer Res. 2003;63:7443–7450
- . Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways. Clin. Cancer Res. 2003;9:2316–2326
- . Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3′-kinase/Akt pathway signaling. Clin. Cancer Res. 2003;9:4340–4346
- Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. Cancer Res. 2000;60:2926–2935
- . ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase. Cancer Res. 2002;62:2554–2560
- Influence of epidermal growth factor receptor (EGFR), p53 and intrinsic MAP kinase pathway status of tumour cells on the antiproliferative effect of ZD1839 (“Iressa”). Br. J. Cancer. 2002;86:1518–1523
- The sensitivity of lung cancer cell lines to the EGFR-selective tyrosine kinase inhibitor ZD1839 (’Iressa’) is not related to the expression of EGFR or HER-2 or to K-ras gene status. Lung Cancer. 2003;42:35–41
- Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. Clin. Cancer Res. 2000;6:2053–2063
- . The role of erlotinib (Tarceva OSI 774) in the treatment of non-small cell lung cancer. Clin. Cancer Res. 2004;15:4238s–4240s
- . Inhibition of proliferation and induction of apoptosis in breast cancer cells by the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ZD1839 (’Iressa’) is independent of EGFR expression level. J. Cell. Physiol. 2004;198:259–268
- . ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells. Clin. Cancer Res. 2003;9:1274–1283
- . A histopathologic and immunohistochemical study of prognostic factors in esophageal squamous cell carcinoma. Zhonghua Bing Li Xue Za Zhi. 2000;29:267–271
- . c-erbB-2 oncoprotein expression related to chemoradioresistance in esophageal squamous cell carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 2003;57:1323–1327
PII: S0304-3835(04)00997-8
doi: 10.1016/j.canlet.2004.12.025
© 2005 Elsevier Ireland Ltd. All rights reserved.
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Cancer Letters
Volume 226, Issue 1
, Pages 37-47
, 8 August 2005
