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Cancer Letters
Volume 230, Issue 1
, Pages 33-46
, 8 December 2005
Cooperative cell-growth inhibition by combination treatment with ZD1839 (Iressa) and trastuzumab (Herceptin) in non-small-cell lung cancer
References
- . The EGF receptor family as targets for cancer therapy. Oncogene. 2000;19:6550–6565
- . The ErbB receptor family: a therapeutic target for cancer. Trends Mol. Med. 2002;8:19–26
- . The epidermal growth factor receptor and its inhibition in cancer therapy. Pharmacol. Ther. 1999;82:241–250
- . The ErbB signaling network: receptor heterodimerization in development and cancer. Eur. Mol. Biol. Org. J. 2000;19:3159–3167
- . Epidermal growth factor-related peptides and their receptors in human malignancies. Crit. Rev. Oncol. Hematol. 1995;19:183–232
- . Epidermal growth factor receptor dependence in human tumors: more than just expression. Oncologist. 2002;7:31–39
- . EGFR receptor in neoplasia and metastasis. Cancer Metastasis Rev. 1993;12:255–274
- . Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy. Drugs. 2000;60:15–23
- . ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. Eur. Mol. Biol. Org. J. 1997;16:1647–1655
- . ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer. Eur. Mol. Biol. Org. J. 1996;15:254–264
- . ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases. J. Cell Biol. 2000;148:385–397
- . Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer. Lancet. 1987;1:1398–1402
- Epidermal growth factor receptors and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival. Clin. Cancer Res. 2001;7:1850–1855
- . The relationship of quantitive epidermal growth factor receptor expression in non-small cell lung cancer to long term survival. Br. J. Cancer. 1993;68:162–165
- . A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor. Clin. Cancer Res. 2001;7:1958–1970
- . ZD1839 (‘Iressa’) as an anticancer agent. Drugs. 2000;60:33–40
- . Anticancer drug targets: growth factors and growth factor signaling. J. Clin. Invest. 2000;105:9–13
- . Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily: role as anticancer agents. Drugs. 2000;59:753–767
- Specific inhibition of epidermal growth factor receptor tyrosine kinase by 4-anilinoquinazolines. Breast Cancer Res. Treat. 1996;38:67–73
- Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. Clin. Cancer Res. 2000;6:2053–2063
- Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Clin. Cancer Res. 2001;7:1459–1465
- ZD1839 (Irresa): an orally active inhibitors of epidermal growth factor signaling with potential for cancer therapy. Cancer Res. 2002;62:5749–5754
- . Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), a inhibitor of EGFR tyrosine kinase. Clin. Cancer Res. 2000;6:4885–4892
- . A multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (the IDEAL 1 trial). J. Clin. Oncol. 2003;21:2237–2241
- . A phase II trial of ZD1839 (‘Iressa’) in advanced non-small cell lung cancer (NSCLC) patients who had failed platinum- and docetaxel-based regimens (IDEAL 2). Proc. Am. Soc. Clin. Oncol. 2002;21:292
- . Targeting the epidermal growth factor receptor-tyrosine kinase inhibitors: small molecules, big hopes. J. Clin. Oncol. 2002;20:2217–2219
- Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J. Clin. Oncol. 2003;21:2237–2246
- . Monoclonal antibody therapy of human cancer: taking the HER2 protooncogene to the clinic. J. Clin. Immunol. 1991;11:117–127
- . ErbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with ErbB-2 oncogene amplification. Br. J. Cancer. 1994;70:819–825
- . Inhibition of ErbB-2-positive breast cancer cell growth by ErbB-2 antisense oligonucleotides. Antisense Nucleic Acid Drug Dev. 1996;6:9–16
- . Down-relgulation of HER2/neu expression induces apoptosis in human cancer cells that overexpress HER2/neu. Cancer Res. 2000;60:560–565
- . Phasa II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J. Clin. Oncol. 1996;14:737–744
- . Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J. Clin. Oncol. 1998;16:2659–2671
- . Moleclular target-based cancer therapy: epidermal growth factor receptor inhibitors. Jpn. J. Surg. 2002;2:233–236
- . The tyrosine kinase inhibitor ZD1839 (‘Iressa’) inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells. Cancer Res. 2001;61:7184–7188
- . Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Irresa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Cancer Res. 2001;61:8887–8895
- Cooperative inhibitory effect of ZD1839 (Iressa) in combination with trastuzumab (Herceptin) on human breast cancer cell growth. Ann. Oncol. 2002;13:65–72
- . Inhibition by ZD1839 (Iressa) of epidermal growth factor (EGF) and heregulin induced signaling pathways in human breast cancer cells. Proc. Am. Soc. Clin. Oncol. 2001;20:1712A
- . Epidermal growth factor receptors in breast cancer: association with early relapse and death, poor response to hormones and interactions with neu. J. Steroid Biochem. 1989;34:123–131
- . Prognostic significance of co-expression of c-ErbB-2 oncoprotein and epidermal growth factor receptor in breast cancer patients. Am. J. Surg. 1992;164:323–326
- . Relationship between c-ErbB-2 oncoprotein, epidermal growth factor receptor, and estrogen receptor expression in patients with ductal breast carcinoma. Association with tumor phenotypes. In Vivo. 1996;10:217–222
- Sensitivity to gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/Akt pathway for proliferation. Mol. Cancer Ther. 2004;3:465–472
- ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells. Clin. Cancer Res. 2003;9:1274–1283
- . ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without ErbB2 overexpression. Int. J. Cancer. 2001;94:774–782
- . Augmentation of a humanized anti-HER2 monoclonal antibody 4D5 induced growth inhibition by a human-mouse chimeric anti-EGF receptor monoclonal antibody C225. Oncogene. 1999;18:731–738
- Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 2004;350:2129–2139
- EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004;304:1497–1500
- Lung cancer: intragenic ERBB2 kinase mutations in tumors. Nature. 2004;431:525–526
- The sensitivity of lung cancer cell lines to the EGFR-selective tyrosine kinase inhibitor ZD1839 (‘Iressa’) is not related to the expression of EGFR or HER-2 or to K-ras gene status. Lung Cancer. 2003;42:35–41
- . Response to epidermal growth factor receptor inhibits in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways. Clin. Cancer Res. 2003;9:2316–2326
☆ Iressa is a trademark of the AstraZeneca group of companies.
PII: S0304-3835(04)00995-4
doi: 10.1016/j.canlet.2004.12.020
© 2005 Elsevier Ireland Ltd. All rights reserved.
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Cancer Letters
Volume 230, Issue 1
, Pages 33-46
, 8 December 2005
