Cancer Letters
Volume 229, Issue 1 , Pages 1-11 , 8 November 2005

Expression of base excision DNA repair genes as a biomarker of oxidative DNA damage

Received 25 November 2004 ,Accepted 1 December 2004.

References 

  1. Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. Fed. Am. Soc. Exp. Biol. J. 2003;17:1195–1214
  2. von Sonntag C. The Chemical Basis of Radiation Biology. London: Taylor and Francis; 1987;
  3. Friedberg EC. DNA damage repair. Nature. 2003;421:436–440
  4. Slupphaug G, Kavli B, Krokan HE. The interacting pathways for prevention and repair of oxidative DNA damage. Mutat. Res. 2003;531:231–251
  5. Sies H. Oxidative Stress. New York: Academic Press; 1985;
  6. Helbock HJ, Beckman KB, Shigenaga MK, Walter PB, Woodall AA, Yeo HC, et al. DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine. Proc. Natl Acad. Sci. USA. 1998;95:288–293
  7. Kawanishi S, Hiraku Y, Oikawa S. Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging. Mutat. Res. 2001;488:65–76
  8. Marnett LJ. Oxyradicals and DNA damage. Carcinogenesis. 2000;21:361–370
  9. Fraga CG, Shigenaga MK, Park JW, Degan P, Ames BN. Oxidative damage to DNA during aging: 8-hydroxy-2′-deoxyguanosine in rat organ DNA and urine. Proc. Natl Acad. Sci. USA. 1990;87:4533–4537
  10. von Sonntag C. New aspects in the free-radical chemistry of pyrimidine nucleobases. Free Rad. Res. Commun. 1987;2:217–224
  11. Dizdaroglu M. Oxidative damage to DNA in mammalian chromatin. Mutat. Res. 1992;275:331–342
  12. Demple B, Harrison L. Repair of oxidative damage to DNA: enzymology and biology. Annu. Rev. Biochem. 1994;63:915–948
  13. Cadet J, Douki T, Gasparutto D, Ravanat JL. Oxidative damage to DNA: formation, measurement and biochemical features. Mutat. Res. 2003;531:5–23
  14. Hussain SP, Hofseth LJ, Harris CC. Radical causes of cancer. Nat. Rev. Cancer. 2003;3:276–285
  15. Collins AR. Oxidative DNA damage, antioxidants, and cancer. Bioessays. 1999;21:238–246
  16. ESCODD . Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus. Carcinogenesis. 2002;23:2129–2133
  17. ESCODD . Measurement of DNA oxidation in human cells by chromatographic and enzymic methods. Free Radic. Biol. Med. 2003;34:1089–1099
  18. Friedberg EC, Walker GC, Siede W. DNA Repair and Mutagenesis. Washington, DC: American Society for Microbiology; 1995;
  19. Scharer OD, Jiricny J. Recent progress in the biology, chemistry and structural biology of DNA glycosylases. Bioessays. 2001;23:270–281
  20. Wood RD, Mitchell M, Sgouros J, Lindahl T. Human DNA repair genes. Science. 2001;291:1284–1289
  21. Samson L, Cairns J. A new pathway for DNA repair in Escherichia coli. Nature. 1977;267:281–283
  22. Halliwell B, Aruoma OI. DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. Fed. Eur. Biochem. Soc. Lett. 1991;281:9–19
  23. Dizdaroglu M. Quantitative determination of oxidative base damage in DNA by stable isotope-dilution mass spectrometry. Fed. Eur. Biochem. Soc. Lett. 1993;315:1–6
  24. Steenken S. Structure, acid/base properties and transformation reactions of purine radicals. Free Rad. Res. Commun. 1989;6:117–120
  25. von Sonntag C. The Chemical Basis of Radiation Biology. London: Taylor and Francis; 1987;
  26. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. Oxford: Clarendon Press; 1989;
  27. Michaels ML, Miller JH. The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine). J. Bacteriol. 1992;174:6321–6325
  28. Thomas D, Scot AD, Barbey R, Padula M, Boiteux S. Inactivation of OGG1 increases the incidence of G:C to T:A transversions in Saccharomyces cerevisiae: evidence for endogenous oxidative damage to DNA in eukaryotic cells. Mol. Gen. Genet. 1997;254:171–178
  29. Inoue S, Kawanishi S. Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide. Fed. Eur. Biochem. Soc. Lett. 1995;371:86–88
  30. Yermilov V, Rubio J, Ohshima H. Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination. Fed. Eur. Biochem. Soc. Lett. 1995;376:207–210
  31. Salgo MG, Stone K, Squadrito GL, Battista JR, Pryor WA. Peroxynitrite causes DNA nicks in plasmid pBR322. Biochem. Biophys. Res. Commun. 1995;210:1025–1030
  32. Douki T, Cadet J. Peroxynitrite mediated oxidation of purine bases of nucleosides and isolated DNA. Free Radic. Res. 1996;24:369–380
  33. Tretyakova NY, Wishnok JS, Tannenbaum SR. Peroxynitrite-induced secondary oxidative lesions at guanine nucleobases: chemical stability and recognition by the Fpg DNA repair enzyme. Chem. Res. Toxicol. 2000;13:658–664
  34. Uppu RM, Cueto R, Squadrito GL, Salgo MG, Pryor WA. Competitive reactions of peroxynitrite with 2′-deoxyguanosine and 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-oxodg) - relevance to the formation of 8-oxodG in DNA exposed to peroxynitrite. Free Radic. Biol. Med. 1996;21:407–411
  35. Burney S, Niles JC, Dedon PC, Tannenbaum SR. DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite. Chem. Res. Toxicol. 1999;12:513–520
  36. Juedes MJ, Wogan GN. Peroxynitrite-induced mutation spectra of pSP189 following replication in bacteria and in human cells. Mutat. Res. 1996;349:51–61
  37. Dedon PC, Plastaras JP, Rouzer CA, Marnett LJ. Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal. Proc. Natl Acad. Sci. USA. 1998;95:11113–11116
  38. Cheeseman KH. Lipid Peroxidation and Cancer. In:  Halliwell B,  Aruoma OI editor. DNA and Free Radicals. Chichester: Ellis Horwood Limited; 1993;p. 109–144
  39. Kaneko T, Honda S, Nakano S, Matsuo M. Lethal effects of a linoleic acid hydroperoxide and its autoxidation products, unsaturated aliphatic aldehydes, on human diploid fibroblasts. Chem. Biol. Interact. 1987;63:127–137
  40. Singer B. The Role of Cyclic Nucleic Acid Adducts in Carcinogenesis and Mutagenesis. vol. 70. IARC Science Publication; 1986;
  41. Marnett LJ. DNA Adducts: Identification and Biological Significance. vol. 125. IARC Science Publication; 1994;
  42. Esterbauer H, Eckl P, Ortner A. Possible mutagens derived from lipids and lipid precursors. Mutat. Res. 1990;238:223–233
  43. Spalding JW. Toxicology and carcinogenesis studies of malondialdehyde sodium salt (3-hydroxy-2-propenal, sodium salt) in F344/N rats and B6C3F1 mice. NTP Technical Report. 1988;331
  44. Armitage P, Doll R. The age distribution of cancer and a multi-stage theory of carcinogenesis. Br. J. Cancer. 1954;8:1–12
  45. Schwarz M, Peres G, Kunz W, Furstenberger G, Kittstein W, Marks F. On the role of superoxide anion radicals in skin tumour promotion. Carcinogenesis. 1984;5:1663–1670
  46. Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420:860–867
  47. Rusyn I, Rose ML, Bojes HK, Thurman RG. Novel role of oxidants in the molecular mechanism of action of peroxisome proliferators. Antiox. Redox. Signal. 2000;2:607–621
  48. Cerutti PA, Trump BF. Inflammation and oxidative stress in carcinogenesis. Cancer Cells. 1991;3:1–7
  49. Weisburger JH. Antimutagenesis and anticarcinogenesis, from the past to the future. Mutat. Res. 2001;480–481:23–35
  50. Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow?. Lancet. 2001;357:539–545
  51. Klaunig JE, Xu Y, Bachowski S, Jiang J. Free-radical oxygen-induced changes in chemical carcinogenesis. In:  Wallace KB editors. Free Radical Toxicology. London: Taylor and Francis; 1997;p. 375–400
  52. IARC Working Group, Benzene, IARC Monographs on the evaluation of the carcinogenic risk of chemicals in humans, 7 (1987).
  53. Kolachana P, Subrahmanyam VV, Meyer KB, Zhang L, Smith MT. Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo. Cancer Res. 1993;53:1023–1026
  54. Goode EL, Ulrich CM, Potter JD. Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol. Biomarkers Prev. 2002;11:1513–1530
  55. Tomkinson AE, Mackey ZB. Structure and function of mammalian DNA ligases. Mutat. Res. 1998;407:1–9
  56. Cairns J. The contribution of bacterial hypermutators to mutation in stationary phase. Genetics. 2000;156:923–926
  57. Glassner BJ, Rasmussen LJ, Najarian MT, Posnick LM, Samson LD. Generation of a strong mutator phenotype in yeast by imbalanced base excision repair. Proc. Natl Acad. Sci. USA. 1998;95:9997–10002
  58. Posnick LM, Samson LD. Imbalanced base excision repair increases spontaneous mutation and alkylation sensitivity in Escherichia coli. J. Bacteriol. 1999;181:6763–6771
  59. Canitrot Y, Cazaux C, Frechet M, Bouayadi K, Lesca C, Salles B, et al. Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs. Proc. Natl Acad. Sci. USA. 1998;95:12586–12590
  60. Collins A, Cadet J, Epe B, Gedik C. Problems in the measurement of 8-oxoguanine in human DNA, Report of a workshop, DNA oxidation, held in Aberdeen, UK, 19–21 January 1997. Carcinogenesis. 1997;18:1833–1836
  61. Hofer T, Moller L. Reduction of oxidation during the preparation of DNA and analysis of 8-hydroxy-2′-deoxyguanosine. Chem. Res. Toxicol. 1998;11:882–887
  62. (ESCODD) European Standards Committee on Oxidative DNA Damage . Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus. Carcinogenesis. 2002;23:2129–2133
  63. Jeong YC, Sangaiah R, Nakamura J, Pachkowski BF, Ranasinghe A, Gold A, et al. Analysis of M1G-dR in DNA by ARP Labeling and LC-MS/MS. Chem. Res. Toxicol. 2004;
  64. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 1988;175:184–191
  65. McKelvey-Martin VJ, Green MHL, Schmezer P, Pool-Zobel BL, de Méo MP, Collins A. The single cell gel electrophoresis assay (comet assay): A European review. Mutat. Res. 1993;288:47–63
  66. Nakamura J, Swenberg JA. Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues. Cancer Res. 1999;59:2522–2526
  67. Klaunig JE, Xu Y, Isenberg JS, Bachowski S, Kolaja KL, Jiang J, et al. The role of oxidative stress in chemical carcinogenesis. Environ. Health Perspect. 1998;106(Suppl 1):289–295
  68. Helbock HJ, Beckman KB, Shigenaga MK, Walter PB, Woodall AA, Yeo HC, et al. DNA oxidation matters—the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine. Proc. Natl Acad. Sci. USA. 1998;95:288–293
  69. Reddy JK, Azarnoff DL, Hignite CE. Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature. 1980;283:397–398
  70. Rusyn I, Asakura S, Pachkowski B, Bradford BU, Denissenko MF, Peters JM, et al. Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: Identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators. Cancer Res. 2004;64:1050–1057
  71. Jungst C, Cheng B, Gehrke R, Schmitz V, Nischalke HD, Ramakers J, et al. Oxidative damage is increased in human liver tissue adjacent to hepatocellular carcinoma. Hepatology. 2004;39:1663–1672
  72. Hofseth LJ, Khan MA, Ambrose M, Nikolayeva O, Xu-Welliver M, Kartalou M, et al. The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. J. Clin. Invest. 2003;112:1887–1894
  73. Ichinose T, Yajima Y, Nagashima M, Takenoshita S, Nagamachi Y, Sagai M. Lung carcinogenesis and formation of 8-hydroxy-deoxyguanosine in mice by diesel exhaust particles. Carcinogenesis. 1997;18:185–192
  74. Sagai M, Saito H, Ichinose T, Kodama M, Mori Y. Biological effects of diesel exhaust particles I. In vitro production of superoxide and in vivo toxicity in mouse. Free Radic. Biol. Med. 1993;14:37–47
  75. Ball JC, Straccia AM, Young WC, Aust AE. The formation of reactive oxygen species catalyzed by neutral, aqueous extracts of NIST ambient particulate matter and diesel engine particles. J. Air Waste Manag. Assoc. 2000;50:1897–1903
  76. Huggins FE, Huffman GP, Robertson JD. Speciation of elements in NIST particulate matter SRMs 1648 and 1650. J. Hazard. Mater. 2000;74:1–23
  77. Li XY, Gilmour PS, Donaldson K, MacNee W. In vivo and in vitro proinflammatory effects of particulate air pollution (PM10). Environ. Health Perspect. 1997;105(Suppl 5):1279–1283
  78. Tsurudome Y, Hirano T, Yamato H, Tanaka I, Sagai M, Hirano H, et al. Changes in levels of 8-hydroxyguanine in DNA, its repair and OGG1 mRNA in rat lungs after intratracheal administration of diesel exhaust particles. Carcinogenesis. 1999;20:1573–1576

PII: S0304-3835(04)00965-6

doi: 10.1016/j.canlet.2004.12.002

Cancer Letters
Volume 229, Issue 1 , Pages 1-11 , 8 November 2005