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Cancer Letters
Volume 223, Issue 2
, Pages 181-190
, 8 June 2005
Chemopreventive and therapeutic effects of curcumin
References
- . Mechanistic considerations in chemopreventive drug development. J. Cell Biochem. Suppl. 1994;20:1–24
- . Coffee and its chemopreventive components Kahweol and Cafestol increase the activity of O6-methylguanine-DNA methyltransferase in rat liver—comparison with phase II xenobiotic metabolism. Mutat. Res. 2003;522:57–68
- Chemopreventive effects of emodin and cassiamin B in mouse skin carcinogenesis. Cancer Lett. 2002;182:135–139
- . Chemopreventive efficacy of lycopene on 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. Fitoterapia. 2001;72:865–874
- . The chemopreventive compound curcumin is an efficient inhibitor of Epstein-Barr virus BZLF1 transcription in Raji DR-LUC cells. Mol. Carcinog. 2002;33:137–145
- . Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice. Nutr. Cancer. 1992;17:77–83
- . Protective single/combined treatment with betel leaf and turmeric against methyl (acetoxymethyl) nitrosamine-induced hamster oral carcinogenesis. Int. J. Cancer. 1992;51:412–415
- . Chemopreventive effects of curcumin on glandular stomach carcinogenesis induced by N-methyl-N′-nitro-N-nitrosoguanidine and sodium chloride in rats. Anticancer Res. 2001;21:3407–3411
- . Anticarcinogenic effect of bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione a curcumin analog on DMH-induced colon cancer model. Pharmacol. Res. 2003;47:133–140
- . No prevention of liver and kidney tumors in Long-Evans Cinnamon rats by dietary curcumin, but inhibition at other sites and of metastases. Mutat. Res. 2003;523/524:127–135
- Curcumin is an in vivo inhibitor of angiogenesis. Mol. Med. 1998;4:376–383
- . Molecular mechanisms of anti-angiogenic effect of curcumin. Biochem. Biophys. Res. Commun. 2002;297:934–942
- Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res. 2001;21:2895–2900
- . Curcumin exerts multiple suppressive effects on human breast carcinoma cells. Int. J. Cancer. 2002;98:234–240
- . Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line. Cancer Lett. 2002;184:1–6
- . Inhibition of growth and sensitization to cisplatin-mediated killing of ovarian cancer cells by polyphenolic chemopreventive agents. J. Cell Physiol. 2003;194:63–70
- . Induction of apoptosis in tumor cells by natural phenolic compounds. Asian Pac. J. Cancer Prev. 2002;3:61–67
- . Curcumin-induced apoptosis in scleroderma lung fibroblasts: role of protein kinase cepsilon. Am. J. Respir. Cell Mol. Biol. 2004;31:28–35
- Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt. Carcinogenesis. 2003;24:1199–1208
- . Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53. Exp. Cell. Res. 2001;271:305–314
- . Cigarette smoke condensate activates nuclear transcription factor-kappaB through phosphorylation and degradation of IkappaB(alpha): correlation with induction of cyclooxygenase-2. Carcinogenesis. 2002;23:1511–1518
- . Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells. J. Agric. Food Chem. 2001;49:1464–1474
- . Ruthenium red, inhibitor of mitochondrial Ca2+uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+depletion and cytochrome c release. Biochem. Biophys. Res. Commun. 2003;303:1073–1079
- . Curcumin induces caspase-3-independent apoptosis in human multidrug-resistant cells. Ann. NY Acad. Sci. 2002;973:250–254
- . Effect of glutathione depletion on caspase-3 independent apoptosis pathway induced by curcumin in Jurkat cells. Free Radic. Biol. Med. 2001;31:670–678
- A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells. Exp. Cell Res. 1999;249:299–307
- . Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases. Fed. Eur. Biochem. Soc. Lett. 2003;538:19–24
- . Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway. J. Biol. Chem. 2004;279:11680–11685
- . Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res. 2002;62:3868–3875
- . Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res. 1991;51:813–819
- . Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy?. Biochem. Pharmacol. 2001;62:1433–1438
- . Protective effects of curcumin against oxidative damage on skin cells in vitro: its implication for wound healing. J. Trauma. 2001;51:927–931
- . The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. 2001;21:8370–8377
- . Curcumin ameliorates ethanol and nonethanol experimental pancreatitis. Am. J. Physiol. Gastrointest Liver Physiol. 2003;284:G85–G95
- . Effect of curcumin on galactose-induced cataractogenesis in rats. Mol. Vis. 2003;9:223–230
- Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition. Biochem. Pharmacol. 2003;66:1475–1483
- . Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and Ikappa Balpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood. 2003;101:1053–1062
- The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-kappa B. Thromb. Haemost. 1997;77:772–782
- . Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells. J. Biochem. Mol. Biol. 2002;35:337–342
- . Inhibition of tissue factor gene activation in cultured endothelial cells by curcumin. Suppression of activation of transcription factors Egr-1, AP-1, and NF-kappa B. Arterioscler Thromb. Vasc. Biol. 1997;17:3406–3413
- . Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-kappaB and AP-1. Biofactors. 2000;12:107–112
- . Curcumin inhibits IL1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cells. Hematopathol. Mol. Hematol. 1997;11:49–62
- . Basal levels and patterns of anticancer drug-induced activation of nuclear factor-kappaB (NF-kappaB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells. Biochem. Pharmacol. 2002;63:1709–1716
- . Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1. Carcinogenesis. 2003;24:1269–1279
- . Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes. Am. J. Physiol. Gastrointest. Liver Physiol. 2003;284:G321–G327
- . Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin. Oncogene. 1998;17:173–178
- . Curcumin attenuates DNB-induced murine colitis. Am. J. Physiol. Gastrointest. Liver Physiol. 2003;285:G235–G243
- . Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells. J. Cell Biochem. 2003;89:1–5
- Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells. Biochem. Pharmacol. 2003;65:361–376
- . Protein kinase C signaling and oxidative stress. Free Radic. Biol. Med. 2000;28:1349–1361
- . Curcumin is a non-competitive and selective inhibitor of phosphorylase kinase. Fed. Eur. Biochem. Soc. Lett. 1994;341:19–22
- . Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin. J. Cell Biochem. 1997;(Suppl. 28–29):39–48
- . Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells. Carcinogenesis. 1993;14:857–861
- . Curcumin alters EpRE and AP-1 binding complexes and elevates glutamate-cysteine ligase gene expression. Fed. Am. Soc. Exp. Biol. J. 2003;17:473–475
- . Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes. J. Immunol. 2002;168:6506–6513
- Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. Biochem. J. 2003;371:887–895
- . Mechanism of heme oxygenase-1 gene induction by curcumin in human renal proximal tubule cells. Am. J. Physiol. Renal. Physiol. 2001;281:F851–F859
- . Protective effect of curcuminoids on epidermal skin cells under free oxygen radical stress. Planta. Med. 1997;63:265–266
- . Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo. Food Chem. Toxicol. 2001;39:541–547
- . Action of curcumin on the cytochrome P450-system catalyzing the activation of aflatoxin B1. Chem. Biol. Interact. 1996;100:41–51
- . Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells. Biochem. Pharmacol. 1998;56:197–206
- Curcumin activates the aryl hydrocarbon receptor yet significantly inhibits (−)-benzo(a)pyrene-7R-trans-7,8-dihydrodiol bioactivation in oral squamous cell carcinoma cells and oral mucosa. Cancer Res. 2002;62:5451–5456
- . Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity. Pharmacol. Toxicol. 2003;92:33–38
- . Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver. Int. J. Biochem. Cell Biol. 1998;30:445–456
- . Inhibition of glutathione S-transferase activity in human melanoma cells by alpha,beta-unsaturated carbonyl derivatives. Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, curcumin, ethacrynic acid, and trans-2-hexenal. Chem. Biol. Interact. 1996;102:117–132
- . Curcumin-induced cell death in two leukemia cell lines: K562 and Jurkat. Ann. NY Acad. Sci. 2003;1010:389–392
- . Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver. Biochem. Pharmacol. 1996;51:39–45
- . Suppression of altered hepatic foci development by curcumin in wistar rats. Nutr. Cancer. 2003;45:53–59
- . Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat. Res. 1999;428:305–327
PII: S0304-3835(04)00723-2
doi: 10.1016/j.canlet.2004.09.041
© 2004 Elsevier Ireland Ltd. All rights reserved.
« Previous
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Cancer Letters
Volume 223, Issue 2
, Pages 181-190
, 8 June 2005
