« Previous
Next »
Cancer Letters
Volume 208, Issue 1
, Pages 1-33
, 10 May 2004
Common gene polymorphisms, cancer progression and prognosis
References
- . The hallmarks of cancer. Cell. 2000;100:57–70
- International SNP Map Working Group, A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature. 2001;409:928–933
-
.
Implications of the human genome for understanding human biology and medicine.
J. Am. Med. Assoc. 2001;286:2296–2307
- . Spontaneous regression of cancer: possible mechanisms. In Vivo. 1998;12:571–578
-
In:
Vineis P, Malats N, Lang M, d'Errico A, Caporaso N, Cuzick J, Boffetta P editor. Metabolic Polymorphisms and Susceptibility to Cancer. Lyon: IARC Sci. Publ., 148, IARC; 1999;
- . Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers. Cancer Epidemiol. Biomarkers Prev. 2000;9:3–28
- . Polymorphisms and colorectal tumor risk. Gastroenterology. 2001;121:282–301
- . Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis. Mutat. Res. 2002;506-507:65–77
- . NAD(P)H:quinone oxidoreductase (NQO1) polymorphism, exposure to benzene, and predisposition to disease: a HuGE review. Genet. Med. 2002;4:62–70
- . ERCC2/XPD gene polymorphisms and cancer risk. Mutagenesis. 2002;17:463–469
- . Human DNA repair genes. Environ. Mol. Mutagen. 2001;37:241–283
- . DNA adduct burden and tobacco carcinogenesis. Oncogene. 2002;21:7376–7391
- . Cancer cell cycles. Science. 1996;274:1672–1677
- . Proliferation, cell cycle and apoptosis in cancer. Nature. 2001;411:342–348
-
.
The RB and p53 pathways in cancer.
Cancer Cell. 2002;2:103–112
- Cyclin D1 (CCND1) genotype is associated with tumour grade in sporadic pituitary adenomas. Carcinogenesis. 2001;22:1801–1807
- Cyclin D1 gene polymorphism is associated with an increased risk of urinary bladder cancer. Carcinogenesis. 2002;23:257–264
- Increased risk of prostate cancer associated with AA genotype of cyclin D1 gene A870G polymorphism. Int. J. Cancer. 2003;103:116–120
- Polymorphism within the cyclin D1 gene is associated with prognosis in patients with squamous cell carcinoma of the head and neck. Clin. Cancer Res. 1998;4:2411–2418
- Prognostic significance of cyclin D1 gene (CCND1) polymorphism in epithelial ovarian cancer. Int. J. Gynecol. Cancer. 1999;9:342–347
- . Polymorphisms in cyclin D1 gene and hepatocellular carcinoma. Mol. Carcinog. 2002;33:125–129
- . Cyclin D1 protein expression and gene polymorphism in colorectal cancer. Aberdeen Colorectal Initiative. Int. J. Cancer. 2000;88:77–81
- . Effects of cyclin D1 polymorphism on age of onset of hereditary nonpolyposis colorectal cancer. Cancer Res. 2000;60:249–252
- . The influence of cyclin D1 (CCND1) 870A>G polymorphism and CCND1-thymidylate synthase (TS) gene-gene interaction on the outcome of childhood acute lymphoblastic leukaemia. Pharmacogenetics. 2003;13:577–580
- Cyclin D1 polymorphism and expression in patients with squamous cell carcinoma of the head and neck. Am. J. Pathol. 2001;159:1917–1924
- Analysis of G(1)/S checkpoint regulators in metastatic melanoma. Genes Chromosomes Cancer. 2000;28:404–414
- Clinical course of bladder neoplasms and single nucleotide polymorphisms in the CDKN2A gene. Int. J. Cancer. 2003;104:98–103
- . WAF1 genotype and endometrial cancer susceptibility. Gynecol. Oncol. 1999;72:187–192
- . Associations between common polymorphisms in TP53 and p21WAF1/Cip1 and phenotypic features of breast cancer. Carcinogenesis. 2002;23:311–315
- Age-associated increase of codon 72 arginine p53 frequency in gastric cardia and non-cardia adenocarcinoma. Clin. Cancer Res. 2003;9:2151–2156
- . Association of L-myc polymorphism with lung cancer susceptibility and prognosis in relation to age-selected controls and stratified cases. Lung Cancer. 2002;36:125–132
- . EcoRI polymorphism of the L-myc gene in gastric cancer patients. Eur. J. Gastroenterol. Hepatol. 2002;14:1231–1235
- . Association between restriction fragment length polymorphism of the L-myc gene and susceptibility to gastric cancer. Br. J. Surg. 1998;85:681–684
- L-MYC and GSTM1 polymorphisms are associated with unfavourable clinical parameters of gliomas. J. Exp. Clin. Cancer Res. 2000;19:197–200
- Restriction fragment length polymorphism of the L-myc gene is not a prognostic factor in bladder cancer patients. Br. J. Cancer. 1999;79:1855–1858
- Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia. Lancet. 2002;360:1935–1939
- . Complete genomic sequence of the human retinoblastoma susceptibility gene. Genomics. 1993;17:535–543
- A deletion polymorphism due to Alu–Alu recombination in intron 2 of the retinoblastoma gene: association with human gliomas. Mol. Carcinog. 1997;19:69–73
- Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation. J. Biol. Chem. 2003;278:30339–30347
- . Alternate splicing produces a novel cyclin D1 transcript. Oncogene. 1995;11:1005–1011
- Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer. Oncogene. 2002;21:1928–1933
- . A single nucleotide polymorphism in the 3′ untranslated region of the CDKN2A gene is common in sporadic primary melanomas but mutations in the CDKN2B, CDKN2C, CDK4 and p53 genes are rare. Int. J. Cancer. 2001;95:388–393
- . Novel polymorphism in p21(waf1/cip1) cyclin dependent kinase inhibitor gene: association with human esophageal cancer. Oncogene. 2000;19:323–328
- . Polymorphism of the WAF1 gene is related to susceptibility to cervical cancer in Japanese women. Int. J. Mol. Med. 2001;7:261–264
- . Association between polymorphism in p21(Waf1/Cip1) cyclin-dependent kinase inhibitor gene and human oral cancer. Clin. Cancer Res. 2000;6:2440–2447
- . The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat. Genet. 2003;33:357–365
- Higher lung cancer risk for younger African–Americans with the Pro/Pro p53 genotype. Carcinogenesis. 1995;16:2205–2208
- . The p53 codon 72 polymorphism and lung cancer risk. Cancer Epidemiol. Biomarkers Prev. 2000;9:1037–1042
- . Combinations of the variant genotypes of GSTP1, GSTM1, and p53 are associated with an increased lung cancer risk. Cancer Res. 2002;62:2819–2823
- . Identification and characterization of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) gene. Mol. Immunol. 1997;34:577–582
- . Fas A670G polymorphism, apoptotic capacity in lymphocyte cultures, and risk of lung cancer. Lung Cancer. 2003;42:1–8
- Functional FAS promoter polymorphisms are associated with increased risk of acute myeloid leukemia. Cancer Res. 2003;63:4327–4330
- . The many faces of c-MYC. Arch. Biochem. Biophys. 2003;416:129–136
- . The microenvironment of the tumour-host interface. Nature. 2001;411:375–379
- . Inflammation and cancer. Nature. 2002;420:860–867
-
.
Molecular mechanisms of lymphangiogenesis in health and disease.
Cancer Cell. 2002;1:219–227
- . Axis of evil: molecular mechanisms of cancer metastasis. Oncogene. 2003;22:6524–6536
- . Role of genetic polymorphisms in tumour angiogenesis. Br. J. Cancer. 2002;87:1057–1065
- . Genetic variation in the tumor necrosis factor-alpha promoter region and in the stress protein hsp70-2: susceptibility and prognostic implications in breast carcinoma. Cancer. 2001;91:672–678
- Genetic polymorphisms in the tumor necrosis factor locus influence non-Hodgkin's lymphoma outcome. Blood. 1998;91:3574–3581
- Human leukocyte antigens class II and tumor necrosis factor genetic polymorphisms are independent predictors of non-Hodgkin lymphoma outcome. Blood. 2002;100:3037–3040
- Influence of cytokine gene polymorphisms on the development of prostate cancer. Cancer Res. 2002;62:3369–3372
- . Association of initial response to prednisone treatment in childhood acute lymphoblastic leukaemia and polymorphisms within the tumour necrosis factor and the interleukin-10 genes. Leukemia. 2002;16:1437–1442
- Genetic polymorphisms in the tumour necrosis factor locus in childhood acute lymphoblastic leukaemia. Br. J. Haematol. 2002;119:985–987
- Polymorphisms in tumour necrosis factor (TNF) are associated with risk of bladder cancer and grade of tumour at presentation. Br. J. Cancer. 2003;89:1096–1101
- Polymorphisms of the tumor necrosis factor-alpha gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma. Blood. 2002;100:2263–2265
- The study of tumor necrosis factor beta gene polymorphism in lung cancer patients. Cancer. 1994;73:1184–1188
- 10.5-kb homozygote of tumor necrosis factor-beta gene is associated with a better prognosis in gastric cancer patients. Cancer. 1995;75:1450–1453
- . A polymorphism of the interleukin-1 beta gene influences survival in pancreatic cancer. Br. J. Cancer. 2000;83:1443–1447
- An interleukin-6 gene promoter polymorphism influences the biological phenotype of ovarian cancer. Cancer Res. 2003;63:3066–3068
- Interleukin-6-174G→C polymorphism is associated with improved outcome in high-risk breast cancer. Cancer Res. 2003;63:8051–8056
- . Interleukin-8 (IL-8) promoter region gene polymorphism predicts pelvic recurrence after chemo-radiation in patients with rectal cancer. Int. J. Radiat. Oncol. Biol. Phys. 2003;57:S382
- . IL-10 promoter polymorphisms influence tumour development in cutaneous malignant melanoma. Genes Immun. 2001;2:25–31
- . Interleukin-10, interleukin-6 and interferon-gamma gene polymorphisms in melanoma patients. Melanoma Res. 2002;12:465–469
- . Polymorphisms in the interleukin 10 gene promoter are associated with susceptibility to aggressive non-Hodgkin's lymphoma. Leuk. Lymphoma. 2003;44:251–255
- Genetic polymorphisms of the interleukin-4 receptor alpha gene are associated with an increasing risk and a poor prognosis of sporadic renal cell carcinoma in a Japanese population. Clin. Cancer Res. 2002;8:2620–2625
- . Influence of vascular endothelial growth factor single nucleotide polymorphisms on tumour development in cutaneous malignant melanoma. Genes Immun. 2002;3:229–232
- Association between functional polymorphism in EGF gene and malignant melanoma. Lancet. 2002;359:397–401
- . EGF+61 gene polymorphism and susceptibility to and prognostic markers in cutaneous malignant melanoma. Int. J. Cancer. 2003;107:673–675
- Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele. Cancer Res. 2002;62:840–847
- Insulin-like growth factor-binding protein-3 gene -202 A/C polymorphism is correlated with advanced disease status in prostate cancer. Cancer Res. 2003;63:4407–4411
- Polymorphisms of the endothelial nitric oxide synthase gene in ovarian cancer. Gynecol. Oncol. 2002;86:134–137
- . Endothelial nitric oxide synthase gene polymorphisms and genetic susceptibility to prostate cancer. Eur. J. Cancer Prev. 2002;11:343–350
- . Endothelial nitric oxide synthase gene polymorphisms and the shedding of circulating tumour cells in the blood of prostate cancer patients. Cancer Lett. 2003;189:85–90
- Outcome in prostate cancer: association with endothelial nitric oxide synthase Glu-Asp298 polymorphism at exon 7. Clin. Cancer Res. 2002;8:3433–3437
- Correlation between expression of the matrix metalloproteinase-1 gene in ovarian cancers and an insertion/deletion polymorphism in its promoter region. Cancer Res. 1999;59:4225–4227
- . Invasiveness of cutaneous malignant melanoma is influenced by matrix metalloproteinase 1 gene polymorphism. Cancer Res. 2001;61:1296–1298
- . Matrix metalloproteinase-1 promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness. Clin. Cancer Res. 2001;7:2344–2346
- . A single nucleotide polymorphism in the matrix metalloproteinase-3 promoter enhances breast cancer susceptibility. Clin. Cancer Res. 2002;8:3820–3823
- . A relationship between Matrix metalloproteinase-1 (MMP-1) promoter polymorphism and cervical cancer progression. Cancer Lett. 2003;200:49–55
- . Plasminogen activator inhibitor-1 gene polymorphism and colorectal cancer risk and prognosis. Cancer Lett. 2003;189:189–196
- . Genetic polymorphisms of platelet adhesive molecules: association with breast cancer risk and clinical presentation. Breast Cancer Res. Treat. 2003;80:145–154
- . Association between a C/A single nucleotide polymorphism of the E-cadherin gene promoter and transitional cell carcinoma of the bladder. J. Urol. 2003;170:1379–1382
- . Correlation of a single nucleotide polymorphism in the E-cadherin gene promoter with tumorigenesis and progression of gastric carcinoma in Japan. Int. J. Oncol. 2003;23:421–427
- . Tumour necrosis factor alpha: a potential target for the therapy of solid tumours. Lancet Oncol. 2003;4:565–573
-
D. Hanrahan, J. Folkman, Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis, Cell 86 (1996) 353–364.
- . Angiogenesis in cancer and other diseases. Nature. 2000;407:249–257
- . Vascular-specific growth factors and blood vessel formation. Nature. 2000;407:242–248
- . Vascular endothelial growth factor: its prognostic, predictive, and therapeutic implications. Lancet Oncol. 2001;2:667–673
- . Haplotype analysis of the polymorphic human vascular endothelial growth factor gene promoter. Cancer Res. 2003;63:812–816
- . A common 936 C/T mutation in the gene for vascular endothelial growth factor is associated with vascular endothelial growth factor plasma levels. J. Vasc. Res. 2000;37:443–448
- . Vascular endothelial growth factor gene-460 C/T polymorphism is a biomarker for prostate cancer. Urology. 2003;62:374–377
- A common 936 C/T gene polymorphism of vascular endothelial growth factor is associated with decreased breast cancer risk. Int. J. Cancer. 2003;106:468–471
- A polymorphism in endostatin, an angiogenesis inhibitor, predisposes for the development of prostatic adenocarcinoma. Cancer Res. 2001;61:7375–7378
- . Role of nitric oxide in carcinogenesis and tumour progression. Lancet Oncol. 2001;2:149–156
- . Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets. Int. J. Cancer. 2002;99:157–166
- . The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy. Cancer Metastasis Rev. 2003;22:205–222
- . Urokinase-type plasminogen activator: a potent marker of metastatic potential in human cancers. Biochem. Soc. Trans. 2002;30:207–210
- . Integrin beta3 Leu33Pro homozygosity and risk of cancer. J. Natl Cancer Inst. 2003;95:1150–1157
- A single nucleotide polymorphism in the E-cadherin gene promoter alters transcriptional activities. Cancer Res. 2000;60:873–876
- E-cadherin gene polymorphism and risk of urothelial cancer. Cancer Lett. 2003;195:53–58
- . Single-nucleotide polymorphism in the E-cadherin gene promoter modifies the risk of prostate cancer. Int. J. Cancer. 2002;100:683–685
- Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer. Oncogene. 2002;21:8192–8195
- Association of the -160 C→a promoter polymorphism of E-cadherin gene with gastric carcinoma risk. Cancer. 2002;94:1443–1448
- CDH1 c-160a promotor polymorphism is not associated with risk of stomach cancer. Int. J. Cancer. 2002;101:196–197
- . A systematic review of genetic polymorphisms and breast cancer risk. Cancer Epidemiol. Biomarkers Prev. 1999;8:843–854
- . Heterogeneity of genetic alterations in prostate cancer: evidence of the complex nature of the disease. Hum. Mol. Genet. 2001;10:2313–2318
- . Molecular epidemiology of sporadic breast cancer. The role of polymorphic genes involved in oestrogen biosynthesis and metabolism. Mutat. Res. 2003;544:9–41
- The CAG repeat within the androgen receptor gene and benign prostatic hyperplasia. Urology. 1999;53:121–125
- Significance of the CAG repeat polymorphism of the androgen receptor gene in prostate cancer progression. J. Urol. 2000;164:567–572
- . Shorter CAG repeat length in the androgen receptor gene is associated with more aggressive forms of breast cancer. Breast Cancer Res. Treat. 2000;59:153–161
- . Short androgen receptor allele length is a poor prognostic factor in epithelial ovarian carcinoma. Clin. Cancer Res. 2003;9:3667–3673
- Androgen receptor polymorphisms: association with prostate cancer risk, relapse and overall survival. Int. J. Cancer. 1999;84:458–465
- Correlation of prostate-specific antigen promoter polymorphisms with clinicopathological characteristics in breast cancer. Anticancer Res. 2002;22:1825–1828
- Novel polymorphisms in prostate specific antigen gene and its association with prostate cancer. Anticancer Res. 2001;21:197–200
- . Luteinizing hormone signaling and breast cancer: polymorphisms and age of onset. J. Clin. Endocrinol. Metab. 2003;88:1653–1657
- Association of SRD5A2 genotype and pathological characteristics of prostate tumors. Cancer Res. 2000;60:1626–1630
- Polymorphisms in the androgen receptor and type II 5 alpha-reductase genes and prostate cancer prognosis. Prostate. 2002;52:269–278
- . Codon 89 polymorphism in the human 5 alpha-reductase gene in primary breast cancer. Br. J. Cancer. 2001;84:760–767
- . The V89L polymorphism in the 5-alpha-reductase type 2 gene and risk of breast cancer. Cancer Epidemiol. Biomarkers Prev. 2003;12:1194–1199
- V89L polymorphism of type-2, 5-alpha reductase enzyme gene predicts prostate cancer presence and progression. Urology. 2001;57:199–204
- . TA repeat polymorphism of the 5alpha-reductase gene and breast cancer. Cancer Epidemiol. Biomarkers Prev. 2000;9:387–393
- . A polymorphism in the CYP17 gene increases the risk of breast cancer. Cancer Res. 1997;57:1063–1065
- . CYP17 and breast cancer risk: the polymorphism in the 5′ flanking area of the gene does not influence binding to Sp-1. Cancer Res. 1999;59:2825–2828
- A tetranucleotide repeat polymorphism in CYP19 and breast cancer risk. Int. J. Cancer. 2000;87:204–210
- Progression of human breast cancers to the metastatic state is linked to genotypes of catechol-O-methyltransferase. Cancer Lett. 2000;150:23–31
- . Association of breast cancer progression with a vitamin D receptor gene polymorphism. South-East Sweden Breast Cancer Group. Cancer Res. 1999;59:2332–2334
- . Clinical and pathological significance of vitamin D receptor gene polymorphism for prostate cancer which is associated with a higher mortality in Japanese. Endocr. J. 2001;48:543–549
- . Association of vitamin D receptor gene polymorphism with renal cell carcinoma in Japanese. Endocr. J. 2002;49:433–438
- . Vitamin D receptor gene polymorphism is associated with metastatic breast cancer. Oncol. Res. 1998;10:43–46
- . Vitamin D receptor start codon polymorphism (FokI) and prostate cancer progression. Cancer Epidemiol. Biomarkers Prev. 2003;12:23–27
- . Osteocalcin gene HindIII C/T polymorphism is a biomarker for prostate cancer and responsiveness to hormone therapy. Eur. Urol. 2003;43:197–200
- . Association of breast cancer risk with a GT dinucleotide repeat polymorphism upstream of the estrogen receptor-alpha gene. Cancer Res. 2003;63:5727–5730
- Genetic polymorphisms in the estrogen receptor alpha gene and risk of breast cancer: results from the Shanghai Breast Cancer Study. Cancer Epidemiol. Biomarkers Prev. 2003;12:853–859
- . Estrogen receptor alpha gene polymorphisms and endometrial cancer risk. Carcinogenesis. 2000;21:623–627
- . Polymorphisms of estrogen receptor alpha gene in endometrial cancer. Biochem. Biophys. Res. Commun. 2002;297:558–564
- . Polymorphisms of estrogen receptor alpha in prostate cancer. Mol. Carcinog. 2003;37:202–208
- . Single nucleotide polymorphisms of estrogen receptor alpha in human renal cell carcinoma. Biochem. Biophys. Res. Commun. 2002;296:1200–1206
- . Joint effect of estrogen receptor beta sequence variants and endogenous estrogen exposure on breast cancer risk in Chinese women. Cancer Res. 2003;63:7624–7629
- The progesterone receptor exon 4 Val660Leu G/T polymorphism and risk of breast cancer in Australian women. Cancer Epidemiol. Biomarkers Prev. 2002;11:439–443
- . A functional polymorphism in the progesterone receptor gene is associated with an increase in breast cancer risk. Cancer Res. 2003;63:5236–5238
-
.
A functional polymorphism in the promoter of the progesterone receptor gene associated with endometrial cancer risk.
Proc. Natl Acad. Sci. USA. 2002;99:12263–12268
-
.
Cytochrome P450 polymorphisms as risk factors for steroid hormone-related cancers.
Am. J. Pharmacogenom. 2001;1:83–91
- . Vitamin D and vitamin D analogs as cancer chemopreventive agents. Nutr. Rev. 2003;61:227–238
- . Epidemiologic studies of folate and colorectal neoplasia: a review. J. Nutr. 2002;132:2350S–2355S
- . Common gene polymorphisms and nutrition: emerging links with pathogenesis of multifactorial chronic diseases (review). J. Nutr. Biochem. 2003;14:426–451
- . Pharmacogenetics in cancer treatment. Annu. Rev. Med. 2003;54:437–452
- . Cancer pharmacogenomics: current and future applications. Biochim. Biophys. Acta. 2003;1603:99–111
- . Update on pharmacogenetics in cancer chemotherapy. Eur. J. Cancer. 2002;38:639–644
- . Cancer pharmacogenetics: polymorphisms, pathways and beyond. Nat. Rev. Cancer. 2003;3:912–920
- . Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population. Br. J. Pharmacol. 1998;125:879–887
- Analysis of thiopurine methyltransferase variant alleles in childhood acute lymphoblastic leukaemia. Br. J. Haematol. 1999;105:696–700
- Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J. Natl Cancer Inst. 1999;91:2001–2008
- Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res. 2000;60:6921–6926
- Irinotecan pathway genotype analysis to predict pharmacokinetics. Clin. Cancer Res. 2003;9:3246–3253
- Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene. Clin. Cancer Res. 2000;6:4705–4712
- . Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls. Clin. Cancer Res. 2001;7:2832–2839
- . High prevalence of the IVS14+1G>A mutation in the dihydropyrimidine dehydrogenase gene of patients with severe 5-fluorouracil-associated toxicity. Pharmacogenetics. 2002;12:555–558
- Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate. Ann. Oncol. 2002;13:1915–1918
- Effect of methylenetetrahydrofolate reductase 677C→T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients. Int. J. Cancer. 2003;103:294–299
- . Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy. Clin. Cancer Res. 2003;9:1611–1615
- . Role of polymorphisms in MTHFR and MTHFD1 genes in the outcome of childhood acute lymphoblastic leukemia. Pharmacogenomics J. 2004;4:66–72
- Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer. J. Clin. Oncol. 2001;19:1779–1786
- Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J. 2001;1:65–70
- . A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil. Br. J. Cancer. 2001;85:827–830
- . Thymidylate synthase gene polymorphism predicts response to capecitabine in advanced colorectal cancer. Int. J. Colorectal Dis. 2002;17:46–49
- Polymorphism in the thymidylate synthase promoter enhancer region is not an efficacious marker for tumor sensitivity to 5-fluorouracil-based oral adjuvant chemotherapy in colorectal cancer. Clin. Cancer Res. 2003;9:3700–3704
- New prognostic indicator for non-small-cell lung cancer, quantitation of thymidylate synthase by real-time reverse transcription polymerase chain reaction. Int. J. Cancer. 2003;104:790–795
- . Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia. Blood. 2002;100:3832–3834
- . Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study. Blood. 2000;95:1222–1228
- Glutathione S-transferase GSTM1 and GSTT1 genotypes in ovarian cancer: association with p53 expression and survival. Int. J. Gynecol. Cancer. 2001;11:107–112
- Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer. Cancer Res. 2001;61:7130–7135
- Negative prognostic value of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia. Blood. 2002;100:2703–2707
- Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia. Blood. 2002;100:67–71
- . Polymorphisms within glutathione S-transferase genes and initial response to glucocorticoids in childhood acute lymphoblastic leukaemia. Pharmacogenetics. 2000;10:715–726
- Prognostic significance of the null genotype of glutathione S-transferase-T1 in patients with acute myeloid leukemia: increased early death after chemotherapy. Leukemia. 2002;16:203–208
-
Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapy-induced leukemia.
Proc. Natl Acad. Sci. USA. 2001;98:11592–11597
- . Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. J. Natl Cancer Inst. 2002;94:936–942
- . Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment. Int. J. Cancer. 2003;103:810–814
- . Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer. Cancer Res. 1996;56:3725–3730
- . Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes, DNA repair enzymes, and response to treatment of childhood acute lymphoblastic leukemia. Clin. Cancer Res. 2002;8:802–810
- Association between sulfotransferase 1A1 genotype and survival of breast cancer patients receiving tamoxifen therapy. J. Natl Cancer Inst. 2002;94:1635–1640
- MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res. 2002;62:4955–4962
- . Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast cancer. Int. J. Oncol. 2003;22:1117–1121
- . A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer. Anticancer Res. 2001;21:3075–3079
- . Polymorphisms in the DNA repair gene XRCC1, breast cancer risk, and response to radiotherapy. Cancer Epidemiol. Biomarkers Prev. 2003;12:1168–1174
- . The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia. Blood. 2002;100:3761–3766
- An intron splice acceptor polymorphism in hMSH2 and risk of leukemia after treatment with chemotherapeutic alkylating agents. Clin. Cancer Res. 2003;9:3012–3020
- . A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer. Cancer Res. 2001;61:8654–8658
- . Pharmacogenomics of human UDP-glucuronosyltransferase enzymes. Pharmacogenomics J. 2003;3:136–158
- . Known variant DPYD alleles do not explain DPD deficiency in cancer patients. Pharmacogenetics. 2000;10:217–223
- Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism. Blood. 2001;98:231–234
- . 5-fluorouracil: mechanisms of action and clinical strategies. Nat. Rev. Cancer. 2003;3:330–338
PII: S0304-3835(04)00145-4
doi: 10.1016/j.canlet.2004.02.009
© 2004 Elsevier Ireland Ltd. All rights reserved.
« Previous
Next »
Cancer Letters
Volume 208, Issue 1
, Pages 1-33
, 10 May 2004
