Cancer Letters
Volume 210, Issue 1 , Pages 17-26 , 8 July 2004

Amelioration of ferric nitrilotriacetate (Fe-NTA) induced renal oxidative stress and tumor promotion response by coumarin (1,2-benzopyrone) in Wistar rats

Received 30 September 2003 ,Revised 14 January 2004 ,Accepted 15 January 2004.

References 

  1. Sun Y. Free radicals, antioxidant enzymes and carcinogenesis. Free Rad. Biol. Med. 1990;8:583–599
  2. Anderson RL, Bishop WE, Campbell RL. A review of the environmental and mammalian toxicology of nitrilotriacetic acid. Crit. Rev. Toxicol. 1985;15:1–102
  3. Park JW, Cundy KC, Ames BN. Detection of DNA adducts by HPLC with electrochemical detection. Carcinogenesis. 1989;11:1447–1450
  4. Okada S, Midorikawa O. Induction of rat renal adenocarcinoma by ferric nitrilotriacetate (Fe-NTA). Jpn. Arch. Intern. Med. 1982;29:485–491
  5. Inoue S, Kawanishi S. Hydroxyl radical production and human DNA damage induced by ferric nitrilotriacetate and hydrogen peroxide. Cancer Res. 1987;47:6522–6527
  6. Okada S, Minamiyama Y, Hamazaki S, Toyokuni S, Sotomatsu A. Glutathione cycle dependency of ferric nitrilotriacetate-induced lipid peroxidation in mouse renal proximal tubules. Arch. Biochem. Biophys. 1993;301:138–142
  7. Wattenberg LW, Lam LKT, Fladmose AV. Inhibition of chemical carcinogen induced neoplasia by coumarins and α-angelicalactone. Cancer Res. 1979;39:1651–1654
  8. Khan N, Sharma S, Alam A, Saleem M, Sultana S. Tephrosia purpurea ameliorates N-diethylnitrosamine and potassium bromate-mediated renal oxidative stress and toxicity in Wistar rats. Pharmacol. Toxicol. 2001;88:294–299
  9. Khan N, Sharma S, Sultana S. Nigella sativa ameliorates potassium bromate induced early events of carcinogenesis: diminution of oxidative stress. Hum. Exp. Toxicol. 2003;22:193–203
  10. Egan DA, Kennedy R, Moran E, Thornes RD. The pharmacology, metabolism, analysis and applications of coumarin and coumarin related compounds. Drug Metab. Rev. 1990;22(5):503–529
  11. Feuer G. The metabolism and biological actions of coumarins. In:  Ellis GP,  West GB editor. Progress in Medicinal Chemistry. 10:Amsterdam: North Holland Publishing Company; 1974;p. 85–158
  12. Kelly VP, EllisEmmManson MM, Chanas SA, Moffat GJ, Mc Leod R, Judah DJ. Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione-S-transferase A5 and P1 subunits, and NAD(P)H: quinone oxidoreductase in rat liver. Cancer Res. 2000;60(4):957–969
  13. Awai M, Narasaki M, Yamanoi Y, Seno S. Induction of diabetes in animals by parenteral administration of ferric nitrilotriacetate. A model of experimental hemochromatosis. Am. J. Pathol. 1979;95:663–672
  14. Jollow DJ, Mitchell JR, Zampaglione N, Gillette JR. Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3,4-bromobezene oxide as the hepatotoxic metabolite. Pharmacology. 1974;11:151
  15. Wright JR, Colby HD, Miles PR. Cytosolic factors that affect microsomal lipid peroxidation in lung and liver. Arch. Biochem. Biophys. 1981;206:296–304
  16. Kanter MW. Clinical Chemistry. USA: The Bobber Merill Company; 1975; pp. 80
  17. Hare RS. Endogenous creatinine in serum and urine. Proc. Soc. Exp. Biol. Med. 1950;74:148
  18. Pick A, Keisari Y. Superoxide anion and H2O2 production by chemically elicited peritoneal macrophages-induction by multiple non-phagocytic stimulus. Cell Immunol. 1981;59:301–308
  19. Habig WH, Pabst MJ, Jakoby WB. Glutathione-S-transferases: The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974;249:7130–7139
  20. Mohandas M, Marshall JJ, Duggin GG, Horvath JS, Tiller D. Differential distribution of glutathione and glutathione related enzymes in rabbit kidney. Cancer Res. 1984;44:5086–5091
  21. Carlberg I, Mannervik B. Glutathione level in rat brain. J. Biol. Chem. 1975;250:5475–5480
  22. Orlowski M, Meister A. (-glutamyl cyclotransferase distribution, isozymic forms and specificity. J. Biol. Chem. 1973;248:2836–2844
  23. Claiborne A. Catalase activity. In:  Greenwald RA editors. CRC Handbook of Methods in Oxygen Radical Research. Boca Raton: CRC Press; 1985;p. 283–284
  24. Zaheer N, Tiwari KK, Krishnan PS. Exposure and solubilization of hepatic mitochondrial shunt dehydrogenases. Arch. Biochem. Biophys. 1965;109:646–648
  25. Athar M, Sharma SD, Iqbal M, Sultana S, Pandaya KB, Tripathi IP. Coordination of copper polyamines complex with immidiozoles potentiates its superoxide dismutase mimicking activity and abolishes its interactions with albumin. Biochem. Mol. Biol. Int. 1996;39:813–821
  26. Benson AM, Hunkalar MJ, Talalay P. Increase of NADPH, quinone reductase activity by dietary antioxidant: Possible role in protection against carcinogenesis and toxicity. Proc. Natl Acad. Sci. USA. 1980;77:5116–5220
  27. O'Brien TG, Simsiman RC, Boutwell RK. Induction of the polyamine biosynthetic enzymes in mouse epidermis by tumor promoting agents. Cancer Res. 1975;35:1662–1670
  28. Smart RC, Huang MT, Conney AH. Sn 1,2-diacylglycerols mimic the effects of TPA in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis. Carcinogenesis. 1986;7:1865–1870
  29. Giles KW, Myers A. An improved diphenyl method for the estimation of deoxyribonucleic acid. Nature. 1965;206:93
  30. Lowry OH, Rosenbrough NJ, Farr A, Randall RJ. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951;193:265–275
  31. Aruoma OI. Methodological considerations for characterizing potential antioxidant actions of bioactive components in plant foods. Mut. Res. 2003;523–524:9–20
  32. Kellof GJ. Perspectives on cancer chemoprevention research and drug development. Adv. Cancer Res. 2000;78:199–334
  33. Husain SR, Cillard J, Cillard P. Hydroxyl radical scavenging activity of flavonoids. Phytochemistry. 1987;26:2489–2492
  34. Hoult JR, Paya M. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen. Pharmacol. 1996;27(4):713–722
  35. Feuer G, Kellen JA, Kovaca K. Suppression of 7,12 dimethyl benz (a) anthracene induced breast carcinoma by coumarin in the rat. Oncology (Basel). 1976;33:35–39
  36. Tseng A. Chemoprevention of tumors in MTV-H ras transgenic mice with coumarin. Proc. Am. Assoc. Cancer Res. 1991;32:2257
  37. Chang WS, Lin CC, Chuang SC, Chiang HC. Superoxide anion scavenging effect of coumarins. Am. J. Chin. Med. 1996;24:11–17
  38. Pegg AE, Shantz LM, Colemn CS. Ornithine decarboxylase as a target for chemoprevention. J. Biol. Chem. 1995;22:132–138
  39. De Flora S, Ramel C. Mechanism of inhibition of mutagenesis and carcinogenesis: classification and overview. Mut. Res. 1988;202:285–306

PII: S0304-3835(04)00056-4

doi: 10.1016/j.canlet.2004.01.011

Cancer Letters
Volume 210, Issue 1 , Pages 17-26 , 8 July 2004